ALPHA-HEMOLYSIN

ALPHA-HEMOLYSIN Structure
CAS No.
94716-94-6
Chemical Name:
ALPHA-HEMOLYSIN
Synonyms
α-HeMolysin;ALPHA-TOXIN;ALPHA-HEMOLYSIN;STAPHYLOCOCCUS AUREUS;Staphylococcus piscifermentans;ALPHA-TOXIN, STAPHYLOCOCCUS AUREUS;α-HemolysinfromStaphylococcusaureus;α-Hemolysin (Staphylococcus aureus);α-hemolysin from staphylococcus aureus;A-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS
CBNumber:
CB4384087
Molecular Formula:
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2024/7/2 8:55:09

ALPHA-HEMOLYSIN Properties

storage temp. 2-8°C
solubility H2O: soluble0.49 - 0.51mg/mL
form lyophilized powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H319-H371
Precautionary statements  P260-P264-P270-P302+P352-P305+P351+P338-P308+P311
Hazard Codes  Xn
Risk Statements  22-21/22
Safety Statements  36-36/37
WGK Germany  3

ALPHA-HEMOLYSIN price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H9395 α-Hemolysin from Staphylococcus aureus lyophilized powder, Protein ~60?% by Lowry, ≥10,000?units/mg protein 94716-94-6 1MG ₹59274 2022-06-14 Buy
Product number Packaging Price Buy
H9395 1MG ₹59274 Buy

ALPHA-HEMOLYSIN Chemical Properties,Uses,Production

Uses

ALPHA-HEMOLYSIN was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.

General Description

α-Hemolysin, a pore-forming cytotoxin is an extracellular protein secreted by most strains of pathogenic?Staphylococcus aureus. It is secreted as a water-soluble monomer and is a small β-barrel protein.

Biochem/physiol Actions

α-Hemolysin is selectively hemolytic and the monomeric form binds to a membrane and specific receptors are not required for binding. Upon binding to biological membranes and/or artificial membranes, self-oligomerization occurs, resulting in ring structures (hexameric aggregates) believed to represent transmembrane pores, which are permeable to ions and small metabolites. It has a marked preference for rabbit red blood cells. α-hemolysin stimulates cellular phospholipases and induces a Ca2+?influx. It leads to membrane disruption of the endothelial barrier and leakage of cytoplasmic components and osmotic lysis of the cells. α-hemolysin is implicated in the pathogenesis of sepsis.

ALPHA-HEMOLYSIN Preparation Products And Raw materials

Raw materials

Preparation Products

ALPHA-TOXIN, STAPHYLOCOCCUS AUREUS A-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS α-hemolysin from staphylococcus aureus ALPHA-HEMOLYSIN (STAPHYLOCOCCUS AUREUS)) STAPHYLOCOCCUS AUREUS ALPHA-HEMOLYSIN ALPHA-TOXIN α-HeMolysin Staphylococcus hominis subsp. novobiosepticus Staphylococcus piscifermentans α-HemolysinfromStaphylococcusaureus α-Hemolysin (Staphylococcus aureus) 94716-94-6 Biochemicals and Reagents BioChemical Enzymatic Cell Lysis and Protoplast Preparation Enzymes, Inhibitors, and Substrates Mammalian Biochemicals and Reagents Protein Extracts Proteins and Derivatives