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FTI-276

FTI-276 Structure
CAS No.
170006-72-1
Chemical Name:
FTI-276
Synonyms
FTI-276;ZIXDDEATQSBHHL-BEFAXECRSA-N;FTI-276 trifluoroacetate salt;N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-;N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT
CBNumber:
CB4442484
Molecular Formula:
C21H27N3O3S2
Molecular Weight:
433.59
MOL File:
Mol file
Modify Date:
2024/10/28 23:16:16
Request For Quotation

FTI-276 Properties

Boiling point 715.6±60.0 °C(Predicted)
Density 1.272±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: >5 mg/mL, soluble
form solid
pka 3.54±0.10(Predicted)
color off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

FTI-276 Chemical Properties,Uses,Production

Biochem/physiol Actions

FTI-276 is a highly potent RasCAAX peptidomimetic. FTI-276 antagonizes both H and K-Ras oncogenic signaling. It is an inhibitor of farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM and is an anti-cancer agent.

FTI-276 Preparation Products And Raw materials

Raw materials

Preparation Products

FTI-276 Suppliers

Global( 44)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32080 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52849 58 Inquiry
TargetMol Chemicals Inc. United States 38470 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49979 58 Inquiry
TargetMol Chemicals Inc. +8613564774135 United States 19863 58 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6214 80 Inquiry
RD International Technology Co., Limited 18024082417 China 9272 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24647 58 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
VWR International 800 932 5000 United Kingdom 6548 82 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
TargetMol Chemicals Inc. 58
GIHI CHEMICALS CO.,LIMITED 58
TargetMol Chemicals Inc. 58
United States Biological 80
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
EMD Biosciences, Inc. 66
VWR International 82
N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA FTI-276 FTI-276 trifluoroacetate salt ZIXDDEATQSBHHL-BEFAXECRSA-N L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]- 170006-72-1 C21H27N3O3S2C2HF3O2 C23H28F3N3O5S2