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R(-)-NIGULDIPINE HCL

R(-)-NIGULDIPINE HCL Structure
CAS No.
113145-70-3
Chemical Name:
R(-)-NIGULDIPINE HCL
Synonyms
R(-)-NIGULDIPINE HCL;R(-)-NIGULDIPINE HYDROCHLORIDE (B859-35);(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-(4,4-diphenyl-1-piperidinyl)propylmethy;(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid,3-(4,4-diphenyl-1-piperidinyl)propylmethylesterhydrochloride
CBNumber:
CB4496997
Molecular Formula:
C36H40ClN3O6
Molecular Weight:
646.18
MOL File:
113145-70-3.mol
Modify Date:
2023/4/23 13:52:06
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R(-)-NIGULDIPINE HCL Properties

storage temp. −20°C
solubility methanol: soluble
color pale yellow
optical activity [α]23/D 12.5°, c = 0.14 in methanol(lit.)

SAFETY

Risk and Safety Statements

WGK Germany  3

R(-)-NIGULDIPINE HCL Chemical Properties,Uses,Production

Uses

(R)-(-)-Niguldipine Hydrochloride is a potent chemosensitizer in multidrug resistant cells.

Biological Activity

L-type Ca 2+ channel blocker and α 1A -adrenoceptor antagonist; less active enantiomer.

Biochem/physiol Actions

Less active enantiomer

R(-)-NIGULDIPINE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

R(-)-NIGULDIPINE HCL Suppliers

Global( 13)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry
Shanghai Yubo Biotechnology Co., Ltd. 021-60514606 CHINA 6969 58 Inquiry
Shanghai Huzhen Industrial Co., Ltd. 021-60345367 13916550749 CHINA 6480 58 Inquiry
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 CHINA 6550 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Riedel-de Haen AG 87
SIGMA-RBI 91
Service Chemical Inc. 71
Tocris Bioscience 77
Sigma-Aldrich 80
Shanghai Yubo Biotechnology Co., Ltd. 58
Shanghai Huzhen Industrial Co., Ltd. 58
Shanghai Zeye Biotechnology Co., Ltd. 58
R(-)-NIGULDIPINE HCL R(-)-NIGULDIPINE HYDROCHLORIDE (B859-35) (R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-(4,4-diphenyl-1-piperidinyl)propylmethy (R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid,3-(4,4-diphenyl-1-piperidinyl)propylmethylesterhydrochloride 113145-70-3