Dicloxacillin sodium
- CAS No.
- 13412-64-1
- Chemical Name:
- Dicloxacillin sodium
- Synonyms
- Dicloxacillin sodium;Dicloxacillin sodium CRS;Dicloxacillin Sodium (500 mg);Dicloxacillin Sodium (300 mg);icloxacillinsodiummonohydrate;Dicloxacillin sodium USP/EP/BP;Dicloxacillin Sodium (1189009);DICLOXACILLIN SODIUM WHO(CRM STANDARD);DICLOXACILLIN SODIUM USP(CRM STANDARD);DICLOXACILLIN SODIUM EPD(CRM STANDARD)
- CBNumber:
- CB4679268
- Molecular Formula:
- C19H20Cl2N3NaO6S
- Molecular Weight:
- 512.33
- MOL File:
- 13412-64-1.mol
- Modify Date:
- 2023/9/1 16:14:28
| Melting point | 222-225°C |
|---|---|
| alpha | D20 +127.2° (water) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble in water |
| BRN | 4778711 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 13412-64-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H334-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P302+P352-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-42/43 | |||||||||
| Safety Statements | 22-26-36/37-45 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | XH8925000 | |||||||||
| HS Code | 29411099 | |||||||||
| Toxicity | LD50 in mice (g/kg): 0.9 i.v.; in rats (g/kg): 0.63 i.p.; >5 orally (Gloxhuber) | |||||||||
| NFPA 704 |
|
Dicloxacillin sodium price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D9016 | Dicloxacillin sodium salt monohydrate | 13412-64-1 | 1G | ₹7804.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D9016 | Dicloxacillin sodium salt monohydrate | 13412-64-1 | 5G | ₹24334.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46182 | Dicloxacillin sodium salt hydrate VETRANAL?, analytical standard | 13412-64-1 | 100MG | ₹5369.2 | 2022-06-14 | Buy |
Dicloxacillin sodium Chemical Properties,Uses,Production
Chemical Properties
White to off-white crystalline powder
Uses
Dicloxacillin sodium salt is used in the treatment of staphylococci resistant to penicillin G. Dicloxacillin binds to specific penicillin-binding proteins in the bacterial cell wall and therefore inhibits the last stage of bacterial cell wall synthesis. Cell lysis, mediated by bacterial cell wall autolytic enzymes, is the result. Dicloxacillin may interfere with autolysin inhibitors.
General Description
The substitution of chlorine atoms on both carbons orthoto the position of attachment of the phenyl ring to the isoxazolering is presumed to enhance further the stability ofthe oxacillin congener dicloxacillin sodium, [3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]penicillin sodiummonohydrate (Dynapen, Pathocil, Veracillin) and toproduce high plasma concentrations of it. Its medicinalproperties and use are similar to those of cloxacillinsodium. Progressive halogen substitution, however, alsoincreases the fraction bound to protein in the plasma, potentiallyreducing the concentration of free antibiotic inplasma and tissues. Its medicinal properties and use are thesame as those of cloxacillin sodium.
Dicloxacillin sodium Preparation Products And Raw materials
Raw materials
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Global( 227)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
| Unicorn Pharmachem Private Limited. | 91-22-23483128 | Maharashtra, India | 114 | 58 | Inquiry |
| Anika International Pvt. Limited | 91-11-47289900 | Delhi, India | 94 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Medkem Laboratories | 91-40-23700606 | Andhra Pradesh, India | 297 | 58 | Inquiry |
| Medilink Pharmachem | 91-79-30070133 | Gujarat, India | 58 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| AUROBINDO PHARMA LTD | +91 (40) 6672 1200 | New Delhi, India | 209 | 58 | Inquiry |
| AUROBINDO PHARMA LIMITED | +91 (40) 6672 1200 | New Delhi, India | 144 | 58 | Inquiry |
13412-64-1(Dicloxacillin sodium)Related Search:
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3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLYL PENICILLIN
DICLOXACILLIN SODIUM SALT HYDRATE VETRAN
DICLOXACILLIN SODIUM EPD(CRM STANDARD)
DICLOXACILLIN SODIUM USP(CRM STANDARD)
DICLOXACILLIN SODIUM WHO(CRM STANDARD)
Dicloxacillin monohydrate sodium salt
Dicloxacillin sodium
Sodium 7-[3-(2,6-dichlorophenyl)-5-methyl-oxazol-4-yl]carbonylamino-3,3-dimet hyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylate
4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 6-3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolylcarbonylamino-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S,5R,6R)-
Dicloxacillin sodium monohydrate/Mesterolone
Monosodium (2S,5R,6R)-6-(3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
(2S,5R,6R)-6-[[[3-(2,6-Dichlorophenyl)-5-Methyl-4-isoxazolyl]carbonyl]aMino]-3,3-
diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid SodiuM Salt Hydrate
Dicloxacillin Sodium (500 mg)
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt, hydrate
Dicloxacillin Sodium (300 mg)
Dicloxacillin sodium hydrate solution,100ppm
Dicloxacillin Sodium Salt Monohydrate Standard
Dicloxacillin sodium CRS
icloxacillinsodiummonohydrate
Dicloxacillin sodium USP/EP/BP
Dicloxacillin Sodium (1189009)
Dicloxacillin Sodium hydrate,Dicloxacillin sodium salt,inhibit,Antibiotic,Bacterial,sepsis,peritonitis,Inhibitor,Dicloxacillin Sodium
Sodium (2S,5R,6R)-6-(3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
13412-64-1
3412-64-1
C19H18Cl2N3NaO6S
C19H16Cl2N3O5SNaxH2O
C19H16Cl2N3NaO5SxH2O
C19H17Cl2N3O5SNa
C19H16Cl2N3NaO5SH2O
Diclocil
Peptide Synthesis/Antibiotics
Aromatics
Chiral Reagents
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Sulfur & Selenium Compounds
APIs
A - KAntibiotics
Antibacterial
Antibiotics A to
Antibiotics A-FAntibiotics
Chemical Structure Class
Interferes with Cell Wall SynthesisAntibiotics
Mechanism of Action
Penicillins and Cephalosporins (beta-Lactams)
Spectrum of Activity