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7-Methoxyflavone

7-Methoxyflavone Structure
CAS No.
22395-22-8
Chemical Name:
7-Methoxyflavone
Synonyms
7-METHOXYFLAVONE;7-methoxoyflavone;METHOXYFLAVONE, 7-;7-Methoxyflavone>7-methoxy-2-phenyl-chromone;JR-8980, 7-Methoxyflavone, 97%;7-methoxy-2-phenylchromen-4-one;7-methoxy-2-phenyl-chromen-4-one;7-Methoxy-2-phenyl-4H-benzopyran-4-one;2-Phenyl-7-methoxy-4H-1-benzopyran-4-one
CBNumber:
CB4735474
Molecular Formula:
C16H12O3
Molecular Weight:
252.26
MOL File:
22395-22-8.mol
MSDS File:
SDS
Modify Date:
2024/7/7 20:48:41

7-Methoxyflavone Properties

Melting point 110-112 °C(lit.)
Boiling point 421.2±45.0 °C(Predicted)
Density 1.240±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Sealed in dry,Room Temperature
solubility DMF: 30 mg/ml,DMSO: 15 mg/ml,Ethanol: 5 mg/ml
form powder to crystal
color White to Light yellow
LogP 3.470 (est)
CAS DataBase Reference 22395-22-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
HS Code  29145019
NFPA 704
1
0 0

7-Methoxyflavone price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) M1423 7-Methoxyflavone min. 98.0 % 22395-22-8 1G ₹2400 2022-05-26 Buy
ALFA India ALF-B24850-14 7-Methoxyflavone, 99% 22395-22-8 25g ₹47681 2022-05-26 Buy
TCI Chemicals (India) M1423 7-Methoxyflavone min. 98.0 % 22395-22-8 5G ₹9500 2022-05-26 Buy
ALFA India ALF-B24850-06 7-Methoxyflavone, 99% 22395-22-8 5g ₹10396 2022-05-26 Buy
ALFA India ALF-B24850-03 7-Methoxyflavone, 99% 22395-22-8 1g ₹4300 2022-05-26 Buy
Product number Packaging Price Buy
M1423 1G ₹2400 Buy
ALF-B24850-14 25g ₹47681 Buy
M1423 5G ₹9500 Buy
ALF-B24850-06 5g ₹10396 Buy
ALF-B24850-03 1g ₹4300 Buy

7-Methoxyflavone Chemical Properties,Uses,Production

Description

7-Methoxyflavone is a natural compound and non-steroidal because it binds reversibly with aromatase which is an enzyme that helps produce estrogen through the conversion of androgen (testosterone) to estrogen. It has strong aromatase inhibiting properties, superior bioavailability, and strong resistance to hepatic metabolism/breakdown.

benefits

7-methoxyflavone is popular nowadays as one of the most powerful aromatase inhibitor and testosterone booster. It is isolated from Zornia brasiliensis. It might change how the body breaks down chemicals called hormones. Some people think this might cause the body to have more of the hormone called testosterone. Testosterone can help build muscle, but can also cause serious side effects.

Biological Activity

7-Methoxyflavone is a flavone that has been found in Z. brasiliensis and has diverse biological activities. It inhibits aromatase (IC50 = 1.9 μM in a cell-free assay) and LPS-induced nitric oxide (NO) production by 17.74% in RAW 264.7 macrophages when used at a concentration of 20 μM. 7-Methoxyflavone activates androgen and/or glucocorticoid receptor transcriptional activity in a reporter assay and has antinociceptive effects in the acetic acid-induced writhing test in mice (ED50 = 82.5 μmol/kg).

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7-METHOXYFLAVONE METHOXYFLAVONE, 7- 2-Phenyl-7-methoxy-4H-1-benzopyran-4-one 7-methoxy-2-phenyl-chromen-4-one 7-methoxy-2-phenylchromen-4-one 7-methoxy-2-phenyl-chromone 7-Methoxy-2-phenyl-4H-benzopyran-4-one 7-methoxoyflavone JR-8980, 7-Methoxyflavone, 97% 7-Methoxyflavone> 4H-1-Benzopyran-4-one, 7-methoxy-2-phenyl- TIANFU-CHEM_ 7-Methoxyflavone,22395-22-8 22395-22-8 Heterocyclic Building Blocks Flavonoids Benzopyrans Building Blocks Mono-substituted Flavones Biochemistry Flavonoids Benzopyrans Building Blocks Heterocyclic Building Blocks