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Alizarin

Alizarin Structure
CAS No.
72-48-0
Chemical Name:
Alizarin
Synonyms
Alizarin Red;SULFATED CASTOR OIL;1,2-DIHYDROXYANTHRAQUINONE;CI 58000;Alizarine;Aliazrin;Alizarine Red;TURKEY RED OIL;MORDANT RED 11;C.I. Pigment Red 83
CBNumber:
CB4854164
Molecular Formula:
C14H8O4
Molecular Weight:
240.21
MOL File:
72-48-0.mol
Modify Date:
2024/3/19 15:37:51

Alizarin Properties

Melting point 287 °C
Boiling point 430 °C
Density 1.06 g/mL at 20 °C
refractive index 1.5190 (estimate)
Flash point 430°C subl.
storage temp. Inert atmosphere,Room Temperature
solubility Solubility Virtually insoluble in water; moderately soluble in ethanol, soluble in benzene, toluene, Ixylene, pyridine, acetic acid
form Fine Powder
pka 6.77(at 25℃)
Colour Index 58000
color Orange to orange-brown
PH Range Yellow (5.5) to red (6.8);Red (10.1) to purple (12.1)
PH 5.5~7.2
Water Solubility Soluble in hexane and chloroform. Slightly soluble in water.
λmax 567nm, 609nm
Merck 14,251
BRN 1914037
Stability Stable. Incompatible with strong oxidizing agents, strong bases.
Biological Applications Detecting microorganisms; treating dermatological conditions
Major Application Plasma displays, Antireflective coatings, chemical-mechanical polishing, photoreceptors, glass coatings, paints, anticorrosion coatings, thermoplastics, wood coloring, textiles, pH sensor device, detergent, hair dyes, darkening skin, cosmetics, parasiticide, antifungal agent
InChIKey RGCKGOZRHPZPFP-UHFFFAOYSA-N
LogP 2.479 (est)
CAS DataBase Reference 72-48-0(CAS DataBase Reference)
NIST Chemistry Reference Alizarin(72-48-0)
EPA Substance Registry System Alizarin (72-48-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H317-H318-H410
Precautionary statements  P261-P272-P273-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36-24/25-22
WGK Germany  3
RTECS  YO8300000
TSCA  Yes
HS Code  29146990
NFPA 704
0
1 0

Alizarin price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 122777 Alizarin Dye content 97?% 72-48-0 100G ₹13209 2022-06-14 Buy
Sigma-Aldrich(India) 122777 Alizarin Dye content 97?% 72-48-0 500G ₹62737.2 2022-06-14 Buy
TCI Chemicals (India) D0242 Alizarin 72-48-0 25G ₹3500 2022-05-26 Buy
Product number Packaging Price Buy
122777 100G ₹13209 Buy
122777 500G ₹62737.2 Buy
D0242 25G ₹3500 Buy

Alizarin Chemical Properties,Uses,Production

Chemical Properties

orange-red crystals or powder

History

In ancient times, alizarin was the preferred red dye. Cloth dyed with it has been found in Egyptian tombs dating 6000 years ago. The dye is found in the madder plant, a member of the Rubiaceae family. In 1944 about 35 species of this plant were known, but the use of more sophisticated analytical methods led to the detection of many more species; by 1984 the number had increased to 50. Alizarin is a mordant dye forming various colored coordination complexes with different metallic salts.

Uses

Alizarin is used widely as a prominent red dye for textile facbrics. Alizarin red is now used in biochemical assay to determine quantitatively by colorimetry, the presence of calcific deposition by ce lls of the osteogenic lineage. Alzarine derivatives was evaluated as new inhibitors of the HIV-1 reverse transcriptase associated DNA polymerase and RNase H. Alizarin was also shown to inhibit prolife ration, tumor growth and suppress tumorigenesis in human osteosarcoma and breast cancer cell representative for bone metastasis.

Preparation

(a) 2 – Bromoanthraquinone and Potassium hydroxide heating; (b) 9,10-Dioxo-9,10-dihydroanthracene-2-sulfonic acid (Sodium) and Sodium hydroxide and Sodium nitrate and Sodium chlorate heating; (C) Anthracene-9,10-dione?and Sodium hydroxide and Sodium chlorate and Sodium nitrate heating (GP 186526); (d) in the presence of Sodium nitrite and Sodium hydroxide and Anthracene-9,10-dione?and Sodium nitrate heating (GP 241806245 987); (e) in the Oxidant and Sodium sulfite and the presence of lime, anthracene in a nitrocellulose derivatives and Sodium hydroxide heating (GP 292247); (f) 2 – Anthraquinonesulfonic acid in the presence of air, with the Sodium hydroxide Etanol wetting treatment (GP 287270); (g) 2-Chloroanthracene-9,10-dione Sodium chlorate in the presence of alkali fusion for (USP 1744815); (h) 2-Methylanthracene-9,10-dione in the presence of Oxidant, with Sodium hydroxide treatment (BP 293328).

Definition

alizarin: An orange-red compound,C14H8O4. The compound is a derivativeof anthraquinone, with hydroxylgroups substituted at the 1and 2 positions. It is an importantdyestuff producing red or violetlakes with metal hydroxide.Alizarin occurs naturally as the glucosidein madder. It can be synthesizedby heating anthraquinone withsodium hydroxide.

Purification Methods

Alizarin crystallises from glacial acetic acid or 95% EtOH. It can also be sublimed at 110o/2mm. It is an indicator with max at 452nm (pH 5.8) and 520nm (pH 7.2). [Beilstein 8 IV 3256.]

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alizarinb Alizarine 3B Alizarine B Alizarine Indicator Alizarine L Paste Alizarine Lake Red 2P Alizarine Lake Red 3P Alizarine Lake Red IPX Alizarine NAC Alizarine Paste 20 percent Bluish Alizarine paste 20% bluish 1,2-Dihydroxy-anthrachinon 1,2-dihydroxy-anthraquinon Alizarin,1,2-Dihydroxyanthraquinone, Mordant Red 11 ALIZARIN SOLUTION 0.1% in Methanol Anthraquinonic Alizarin, pure, 97% 100GR Alizarin, pure, 97% 25GR Alizarine Red B Alizarine Red B2 Alizarine Red IP Alizarine Red IPP Alizarine Red L dandcorangeno.15 Deep Crimson Madder 10821 Deep Crimson Madder 10821E deepcrimsonmadder10821 Eljon Madder Eljon Madder M eljonmadder Mitsui Alizarine B Mitsui Alizarine BS mitsuializarineb Pincoffin Sanyo Carmine L2B Sanyo Carmine l2BT sanyocarminel2b sodiumsulforicinoleate Turkey Red ALIZARINPRIMVEROSIDE 1,2-Dihydroxyanthraqhinone Mordant red 11 (C.I. 58000) 1,2-Dihydroxyanthraquinone, Mordant Red 11 1,2-Anthraquinonediol 1,2-dihydroxy-10-anthracenedione 1,2-Dihydroxy-9,10-anthraquinone 1,2-Dihydroxyanthra-9,10-quinone Alizarin, 97%, pure Alizarine Red YP D&C Orange No.15 10-Anthracenedione,1,2-dihydroxy-9 9,10-Anthracenedione, 1,2-dihydroxy- 9,10-Anthracenedione,1,2-dihydroxy- Ailzarin(c.1.No.5800) Alizarin B Alizarin,CI 58000 Alizarina alizarine3b