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Ubiquinol

CAS No.: 992-78-9

Chemical Name:: Ubiquinol

Synonyms: CoQH2-10;Ubiquinol;Ubiquinol 50;Liposomal QH;Water Soluble Q10;Dihydrocoenzyme Q10;Ubiquinol (1705334);Reduced Coenzyme Q10;Reduced ubiquinone-10;Reduced Ubiquinone Q10

CBNumber:: CB51417992

Molecular Formula:: C59H92O4

Molecular Weight:: 865.36

MOL File:: 992-78-9.mol

Modify Date:: 2024/4/8 9:41:42

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Ubiquinol Properties

Melting point	48-49°C
Boiling point	866.9±65.0 °C(Predicted)
Density	0.951±0.06 g/cm3(Predicted)
storage temp.	Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility	Chloroform: soluble
form	A crystalline solid
pka	10.53±0.50(Predicted)
InChIKey	QNTNKSLOFHEFPK-UPTCCGCDSA-N
SMILES	C1(O)=C(OC)C(OC)=C(O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C

SAFETY

Risk and Safety Statements

HS Code	2909500000

Ubiquinol Chemical Properties,Uses,Production

Description

Ubiquinol is a reduced form of coenzyme Q₁₀ (CoQ₁₀; ), which exists in three redox states: fully oxidized (CoQ₁₀/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol). CoQ₁₀ acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc₁ complex. CoQ₁₀ is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.

Chemical Properties

Light Yellow-Orange Solid

benefits

The reduced form of CoQ10, ubiquinol, is a powerful lipid-soluble antioxidant that provides critical antioxidant protection in the lymph and blood throughout the body. Ubiquinol is the only known fat-soluble antioxidant that human cells can synthesize. In its reduced form, ubiquinol coenzyme Q10 plays a significant role in preventing oxidation in both the lipids that make up much of the structure of cellular membranes in cells throughout the body and also in lipoprotein lipids present in circulation. Coenzyme Q10 can also recycle or regenerate other antioxidants such as vitamin E7 and vitamin C. Ubiquinol plays a critical role in mitochondria by protecting mitochondrial membranes and mitochondrial DNA (mtDNA) from free radical damage[1].

Side effects

Coenzyme Q10 supplements appear to be safe and produce few side effects when taken as directed. Mild side effects might include digestive problems such as: Upper abdominal pain, Loss of appetite, Nausea and vomiting, and Diarrhea.
Other possible side effects may include Headaches and dizziness, Insomnia, Fatigue, Skin itching or rashes, and Irritability or agitation.

References

[1] Pelton, Ross. “Coenzyme Q10: A Miracle Nutrient Advances in Understanding.” Integrative medicine 19 2 (2020): 16–20.

Ubiquinol Preparation Products And Raw materials

Raw materials

Preparation Products

Ubiquinol Suppliers

Global( 81)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Leading Chemical and Trading Co.,Ltd	+8615669938129	China	130	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21669	55	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9337	55	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15395	58	Inquiry
Wuhan Nutra Biotechnology Co.,Ltd	+8617786394783	China	300	58	Inquiry
Finetech Industry Limited	+86-27-87465837 +8618971612321	China	9624	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9322	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Leading Chemical and Trading Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
TargetMol Chemicals Inc.	58
AFINE CHEMICALS LIMITED	58
Wuhan Nutra Biotechnology Co.,Ltd	58
Finetech Industry Limited	58
Baoji Guokang Bio-Technology Co., Ltd.	58

What is Ubiquinol?
Ubiquinol, also known as ubiquinol-10, is the fully reduced form of coenzyme Q10. It is produced in mitochondria and has the a....
Apr 11，2024

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2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl -2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl- 1,4-benzenediol Dihydrocoenzyme Q10 Reduced Coenzyme Q10 Reduced Ubiquinone Q10 Ubiquinol 50 UBIQUINOL (Reduced coenzyme Q10) 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-DecaMethyl -2,6,10,14,18 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecenyl]-5,6-dimethoxy-3-methylbenzene-1,4-diol 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecenyl]-5,6-dimethoxy-3-methylhydroquinone Reduced ubiquinone-10 Water Soluble Q10 Ubiquinol,Dihydrocoenzyme Q10 CoQH2-10 1,4-Benzenediol, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl- Ubiquinol ,Ubidecarenone ,Coenzyme Q10 coenzyme Q10 (Ubiquinol) Ubiquinol (1705334) Coenzyme Q10-hydroquinone Ubidecarenone Impurity 8 (Coenzyme Q10 H2) Reduced CoQ10,CoQ10H2, Ubiquinol Ubiquinol Liposomal QH Water-Soluble Ubiquinol Coenzyme Q10 Impurity F 992-78-9 C59H92O4 Aromatics Intermediates & Fine Chemicals Pharmaceuticals Aromatics Compounds