VERATRYLCURCUMINOID

CAS No.: 160096-59-3

Chemical Name:: VERATRYLCURCUMINOID

Synonyms: DiMC;7-bis(3;CHC 004;6-heptadiene-3;Dimethoxycurcumin;Curcumin Dimethoxy;VERATRYLCURCUMINOID;4-dimethoxyphenyl)-1;Dimethoxycurcumin(DMC);Dimethoxycurcumin(DiMC)

CBNumber:: CB51438869

Molecular Formula:: C23H24O6

Molecular Weight:: 396.43

MOL File:: 160096-59-3.mol

Modify Date:: 2024/7/2 8:55:10

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VERATRYLCURCUMINOID Properties

Melting point	130-131 °C(Solv: ethanol (64-17-5))
Boiling point	587.0±50.0 °C(Predicted)
Density	1.169±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:2): 0.30 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.25 mg/ml
form	A crystalline solid
pka	8.06±0.46(Predicted)
color	Yellow to brown

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

VERATRYLCURCUMINOID Chemical Properties,Uses,Production

Description

Dimethoxycurcumin is a derivative of curcumin that has anti-inflammatory and antioxidant activities. It inhibits mitogen-induced proliferation of CD4⁺ T cells, CD8⁺ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-γ induced by concanavalin A in isolated human lymphocytes when used at concentrations ranging from 1 to 10 μM. Dimethoxycurcumin (1-10 μM) inhibits LPS-induced nitric oxide (NO) production and expression of inducible nitric oxide synthase (iNOS) in RAW 264.7 cells. It inhibits hemolysis of isolated human red blood cells (RBCs) induced by AAPH when used at a concentration of 10 μM.

Uses

dimethoxy Curcumin is an analog of curcumin more effective at suppressing HCT116 tumor cells than the parent compound.

VERATRYLCURCUMINOID Preparation Products And Raw materials

Raw materials

Preparation Products

FLLL31

VERATRYLCURCUMINOID Suppliers

Global( 47)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
RD International Technology Co., Limited	18024082417	China	9155	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
RD International Technology Co., Limited	58

VERATRYLCURCUMINOID Spectrum

VERATRYLCURCUMINOID(160096-59-3)¹HNMR

VERATRYLCURCUMINOID Dimethoxycurcumin (1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one Dimethoxycurcumin(DiMC) Dimethoxycurcumin(DMC) 4',4''-O,O-dimethylcurcumin 1;7-BIS(3;4-DIMETHOXYPHENYL)-1;6-HEPTADIENE-3;5-DIONE 4-dimethoxyphenyl)-1 6-heptadiene-3 7-bis(3 DiMC Curcumin Dimethoxy 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-, (1E,6E)- (1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione Dimethoxycurcumin,CHC004,inhibit,Nuclear factor-κB,CHC-004,CHC 004,Nitric oxide synthases,NO Synthase,NF-κB,DiMC,Inhibitor,NOS,Nuclear factor-kappaB CHC 004 160096-59-3