3-(Hydroxymethyl)naphthalen-2-ol
![3-(Hydroxymethyl)naphthalen-2-ol Structure](CAS/GIF/30159-70-7.gif)
- CAS No.
- 30159-70-7
- Chemical Name:
- 3-(Hydroxymethyl)naphthalen-2-ol
- Synonyms
- 3-hydroxymethyl-2-naphthol;3-Hydroxy-2-naphthalenemethanol;3-(Hydroxymethyl)naphthalen-2-ol;2-Naphthalenemethanol,3-hydroxy-;3-Hydroxymethyl-2-hydroxynaphthalene
- CBNumber:
- CB51503187
- Molecular Formula:
- C11H10O2
- Molecular Weight:
- 174.2
- MOL File:
- 30159-70-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2022/12/30 16:20:48
3-(Hydroxymethyl)naphthalen-2-ol Chemical Properties,Uses,Production
Synthesis
3-(hydroxymethyl)naphthalen-2-ol is prepared by reacting;Methyl 3-hydroxy-2-naphthoate with;sodium borohydride in;methanol.Methyl 3-hydroxy-2-naphthoate (100 mg, 0.49 mmol) was dissolved in methanol (7.0 ml) with stirring in a round bottom flask. Sodium borohydride (185 mg, 4.90 mmol) was then added in carefully into the reaction mixture in two portions with an interval time of 3 hours between them and left to react overnight. The resultant mixture was quenched with addition of water followed by extraction with ethyl acetate (3×10 ml). The organic extracts were collected, dried with magnesium sulphate and concentrated in vacuo to give the colourless powder title compound as a colourless powder (82 mg, 96%): mp: 193 – 195 ℃ (Lit.: 186 – 188 ℃);
vmax/cm-1 3379 br. m (O-H), 2844 w (aro. C-H), 1500 s (aro. C=C); δH (300 MHz; DMSO-d6) 9.82 (1H, br. s., OH), 7.80 (1H, s, C(1)H), 7.76 (1H, d, J 8.1, C(5)H or C(8)H), 7.64 (1H, d, J 8.1, C(5)H or C(8)H), 7.33 (1H, ~t, J 7.5, C(6)H or C(7)H), 7.23 (1H, ~t, J 7.5, C(6)H or C(7)H), 7.09 (1H, s, C(4)H), 5.17 (1H, br. s., OH), 4.63 (2H, br. s., C(9)H2); δC (75 MHz; DMSO-d6) 153.1 (Ar-C), 133.3 (Ar-C), 131.8 (Ar-C) 127.7 (Ar-C), 127.3 (Ar-CH), 125.5 (Ar-CH), 125.4 (Ar-CH), 125.3 (Ar-CH), 122.6 (Ar-CH), 107.9 (Ar-CH), 58.6 (C(9)H2); m/z (-ES) 173 (100%, [MH]-), 174 (12%, [M]-).
3-(Hydroxymethyl)naphthalen-2-ol Preparation Products And Raw materials
3-(Hydroxymethyl)naphthalen-2-ol Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 | China | 3725 | 58 | Inquiry |
Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
Combi-Blocks Inc. | 858 635 8950 | United States | 6632 | 69 | Inquiry |
Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 | China | 15527 | 58 | Inquiry |
Energy Chemical | 021-021-58432009 400-005-6266 | China | 44700 | 61 | Inquiry |
Henan Fangding Technology Co., LTD | 15670369782 15670369782 | China | 9839 | 58 | Inquiry |
SuZhou Medinoah Co.,LTD. | 0512-0512-69561983 13914027025 | China | 3501 | 58 | Inquiry |
Zhuhai Aobokai Biomedical Technology Co., Ltd. | 400-0628126 18736790110; | China | 50498 | 58 | Inquiry |
Qingfeng Chem | 18672943286 | China | 439 | 58 | Inquiry |