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DGL

DGL Structure
CAS No.
Chemical Name:
DGL
Synonyms
DGL;LICORICE;Glycyroc;Glycyrrhizde Radix Et Rhizoma
CBNumber:
CB5244593
Molecular Formula:
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2022/12/21 16:56:50

DGL Chemical Properties,Uses,Production

Chemical Properties

Glycyrrhiza glabra is an herbaceous plant native to southern Europe. It grows wild in Eastern Europe. The plant is 1 to 2 m (3 to 7 ft) tall and has a large creeping root (the secondary roots are branched), erect stalk, alternate leaves, violet flowers (from June to July) and kidney-shaped seeds. The parts used are the stolons and roots (at least 2 years old). Most commercial licorice is extracted from varieties of G. glabra. Licorice is intensely sweet. The sweetening power comes from glycyrrhizin, which is 50 times sweeter than sucrose.

Occurrence

Licorice is a shrub found in subtropical climates

Uses

Licorice is a flavoring agent made from dried root portions of glycyrrhiza glabra. The obtainable forms are root, extract powder, and extract. The extract is used in candy, baked goods, and beverages; the major use is in tobacco.

General Description

The most common variety used for medicinal purposes is Glycyrrhiza glabra var. typica. Licorice has been used since Roman times and was described in early Chinese writings. CHEMISTRY The root and rhizomes of the licorice plant contain 5% to 9% of a steroidal glycoside called glycyrrhizin . In the glycoside form, glycyrrhizin is 150 times sweeter than sugar. Also present are triterpenoids, glucose, mannose, and sucrose. Concentrated aqueous extracts may contain 10% to 20% glycyrrhizin.
When the herb is ingested, the intestinal flora catalyze the conversion of glycyrrhizin into glycyrrhetic acid , the pharmacologically active compound. Glycyrrhizin and glycyrrhetic acid possess mild anti-inflammatory properties. Glycyrrhizin appears to stimulate gastric mucus secretion. This may be the origin of the antiulcer properties of licorice. Glycyrrhizin and glycyrrhetic acid do not act directly as steroids. Instead, they potentiate, rather than mimic, endogenous compounds.
Licorice exerts its protective effects on the gastric mucosa by inhibiting two enzymes, 15-hydroxyprostaglandin dehydrogenase and Δ13prostaglandin reductase. Inhibition of these enzymes causes their substrates to increase in concentration, increasing the levels of prostaglandins in the gastric mucosa and causing a cytoprotective effect. The acid also inhibits 11-β-hydroxysteroid dehydrogenase, thus increasing the glucocorticoid concentration in mineralocorticoid- responsive tissues, causing increased sodium retention, potassium excretion, and blood pressure.

Global( 13)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Dideu Medichem Co. Ltd 18192627656 China 2215 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25298 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd 029-81118914 18066712840 China 10011 58 Inquiry
Zhejiang Huida Biotech Co., LTD 0571-0571-89903882 15990081639 China 3705 58 Inquiry
Zhejiang Huida Biotech Co., LTD 0571-89903882 13626641628 China 3657 58 Inquiry
Scandinavian Formulas, Inc. 215 453 2507 United States 1447 55 Inquiry
kemikalieimport + 45 - 2034 3359 Europe 6699 47 Inquiry
ecochem international chemical broker +45 45 42 34 36 Europe 6385 66 Inquiry
AerChem inc. 812-334-9996 United States 364 42 Inquiry
LICORICE DGL Glycyrrhizde Radix Et Rhizoma Glycyroc