1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate

1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate Structure
CAS No.
184764-13-4
Chemical Name:
1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate
Synonyms
Montelukast Impurity 21;Montelukast Keto Impurity;Montelukast KSM-I Keto impurity;Montelukast (3S)-Hydroxy Methylketon;Montelukast (3S)-Hydroxy Methylketone;Montelukast hydroxy methyl ketone impurity;2-Butanone,1-amino-4-hydroxy-,hydrochloride(1:1);1-{2-[(3S)-3-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-hydroxypropyl]phenyl}ethanone;(S,E)-1-(2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl) phenyl)-3-hydroxypropyl)phenyl)ethan-1-one;[S-(E)]-1-[2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone
CBNumber:
CB52508354
Molecular Formula:
C28H24ClNO2
Molecular Weight:
441.95
MOL File:
184764-13-4.mol
Modify Date:
2023/4/23 13:52:06

1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate Properties

Melting point 75-83°C
Boiling point 637.6±55.0 °C(Predicted)
Density 1.256±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
pka 14.07±0.20(Predicted)
form Solid
color White to Pale Yellow

1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

Intermediate in the production of Montelukast metabolites

1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate [S-(E)]-1-[2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone 1-{2-[(3S)-3-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-hydroxypropyl]phenyl}ethanone Montelukast (3S)-Hydroxy Methylketone Montelukast Impurity 21 1-[2-[(3S)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone Montelukast Keto Impurity Montelukast impurity 16/Montelukast (3S)-Hydroxy Methylketone/1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate Ethanone, 1-[2-[(3S)-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]- (S,E)-1-(2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl) phenyl)-3-hydroxypropyl)phenyl)ethan-1-one Montelukast hydroxy methyl ketone impurity 2-Butanone,1-amino-4-hydroxy-,hydrochloride(1:1) Montelukast KSM-I Keto impurity Montelukast (3S)-Hydroxy Methylketon 184764-13-4 C28H24ClNO2 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals