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5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Structure
CAS No.
947502-66-1
Chemical Name:
5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Synonyms
Prasugrel Hydroxy Thiolactone;Prasugrel impurity F;Prasugrel EP Impurity F;Prasugrel impurities1182;Desacetyl hydroxyprasugrel;Prasugrel Hydrochloride EP Impurity F;Prasugrel Hydroxy Thiolactone Desacetyl hydroxyprasugrel;5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-7a-hydroxy-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-one;5-(2-CYCLOPROPYL-1-(2-FLUOROPHENYL)-2-OXOETHYL)-5,6,7,7A-TETRAHYDRO-7A-HYDROXYTHIENO[3,2-C]PYRIDIN-2(4H)-ONE;5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
CBNumber:
CB52655382
Molecular Formula:
C18H18FNO3S
Molecular Weight:
347.4
MOL File:
947502-66-1.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06
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5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Properties

Melting point >45°C (dec.)
Boiling point 547.8±50.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 10.71±0.20(Predicted)
form Solid
color Off-White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS07
Signal word  Warning
Hazard statements  H225-H302+H332-H314
Precautionary statements  P241-P242-P264b-P270-P271-P280-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378r-P403+P233-P501c

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Chemical Properties,Uses,Production

Uses

Prasugrel Hydroxy Thiolactone, is the metabolite of Prasugrel (P701150), which is a novel thienopyridine. It is also a potent inhibitor of platelet aggregation in vivo.

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Suppliers

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KARPSCHEM LABORATORIES 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
Sai Traders 58
BOC Sciences 58
CR Corporation Limited 58
Moxin Chemicals 58
Molcoo Chemicals Inc. 58
Hubei Moco Chemical Co., Ltd. 58

947502-66-1(5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one)Related Search:

Prasugrel IMpurity (1-BroMo-5-chloro-1-(2-fluorophenyl)pentan-2-one) YXSRVOWUJUXDLJ-UHFFFAOYSA-N 1,2-Dihydro-4,6-diMethyl-2-thioxo-3-pyridinecarboxaMide Cyclopropyl 2-fluorobenzyl ketone 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride
Prasugrel alpha-Hydroxy IMpurity trans-R-138727 5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate 5-(2-cyclopropyl-1-(4-fluorophenyl) -2-oxoethyl)-4,5,6,7-tetrahydrothieno [3,2-c]pyridin-2-yl acetate 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2(3H)-one
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Mesna Methyl Ester 2-Bromo Analog DTGLZDAWLRGWQN-GEXSZOTCSA-N Prasugrel Metabolite M5 PRASUGREL METABOLITE R-138727
IZCHRAOWOKMDHU-UHFFFAOYSA-N Cyclopropyl 4-Fluorobenzyl Ketone 2-BroMo-1-cyclopropyl-2-(3-fluorophenyl)ethanone
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5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Prasugrel impurity F 5-(2-CYCLOPROPYL-1-(2-FLUOROPHENYL)-2-OXOETHYL)-5,6,7,7A-TETRAHYDRO-7A-HYDROXYTHIENO[3,2-C]PYRIDIN-2(4H)-ONE 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-7a-hydroxy-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-one Prasugrel impurity 5/Prasugrel Hydroxy Thiolactone/5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one Desacetyl hydroxyprasugrel Thieno[3,2-c]pyridin-2(4H)-one, 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxy- Prasugrel EP Impurity F Prasugrel impurities1182 Prasugrel Hydroxy Thiolactone Prasugrel Hydroxy Thiolactone Desacetyl hydroxyprasugrel Prasugrel Hydrochloride EP Impurity F 947502-66-1