Posaconazole iMpurity

Posaconazole iMpurity Structure
CAS No.
1229428-89-0
Chemical Name:
Posaconazole iMpurity
Synonyms
ent-Posaconazole;Posaconazole IMP;(3R,5S)Posaconazole;Posaconazole Impurity S;2,6-Difluoro Posaconazole;(3R,5S,2R,3R)-posaconazole;posaconazole impurity-89-0;posaconazole impurity-50-5;Posaconazole Impurity(R,S,R,R);Posaconazole Diastereoisomer 14
CBNumber:
CB52686717
Molecular Formula:
C37H42F2N8O4
Molecular Weight:
700.79
MOL File:
1229428-89-0.mol

Posaconazole iMpurity Properties

Boiling point 850.7±75.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 14.72±0.20(Predicted)

Posaconazole iMpurity Chemical Properties,Uses,Production

Uses

ent-Posaconazole is an enantiomer of Posaconazole (P689600), which is an orally active triazole antifungal.

Posaconazole iMpurity Preparation Products And Raw materials

Raw materials

Preparation Products

Posaconazole Diastereoisomer 10 Posaconazole Diastereoisomer 14 Posaconazole IMP 2,6-Difluoro Posaconazole ent-Posaconazole Posaconazole Impurity S (3R,5S,2R,3R)-posaconazole 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl) Posacozole Diastereoisomer 3 (S,R,R,R) 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one D-erythro-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1R,2R)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)- Posaconazole Impurity(R,S,R,R) (3R,5S)Posaconazole posaconazole impurity-89-0 posaconazole impurity-50-5 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one Posaconazole Impurity 10(D-trans:2R,3R) Posaconazole Diastereoisomer 3 RSRR 1229428-89-0 177228-50-5