ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Structure
CAS No.
1593543-00-0
Chemical Name:
(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms
Ezetimibe-19;Ezetimibe Impurity E;Ezetimibe impuritySSR;(3S,4R,3'S)-Ezetimibe;Ezetimibe (SSR)-Isomer;Ezetimibe S,R,S Isomer;Ezetimibe impurities 17;Ezetimibe (SSR) Isomersy;Ezetimibe Impurity 15(SSR);zetimibe (3S,4R,3'S)-Isomer
CBNumber:
CB52735587
Molecular Formula:
C24H21F2NO3
Molecular Weight:
409.43
MOL File:
1593543-00-0.mol
Modify Date:
2023/5/15 10:43:57

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Properties

Boiling point 654.9±55.0 °C(Predicted)
Density 1.334±0.06 g/cm3(Predicted)
solubility Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka 9.72±0.30(Predicted)
color White

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties,Uses,Production

Uses

An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.

(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (3S,4R,3'S)-Ezetimibe zetimibe (3S,4R,3'S)-Isomer Ezetimibe Impurity E Ezetimibe impuriry 20/ (3’S)-ent-Ezetimibe/(3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe-19 Ezetimibe (SSR)-Isomer Ezetimibe impurities 17 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3S,4R)- Ezedrin fabric impurities SSR Ezetimibe impuritySSR Ezetimibe Impurity 15(SSR) Ezetimibe (SSR) Isomersy Ezetimibe (3S,4R,3'S)-Isomer (Ezetimibe Impurity) Ezetimibe S,R,S Isomer Ezetimibe (3S,4R,3'S)-Isomer Ezetimibe (3S,4R,3'S)-Isomer (Ezetimibe Impurity) 1593543-00-0