N-Boc-L-trans-4,5-methanoproline ethyl ester

N-Boc-L-trans-4,5-methanoproline ethyl ester Structure
CAS No.
214193-10-9
Chemical Name:
N-Boc-L-trans-4,5-methanoproline ethyl ester
Synonyms
Saxagliptin Impurity 47;N-Boc-L-trans-4,5-methanoproline Ethyl Ester;Ethyl (1R,3S,5R)-N-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylate;2-(tert-Butyl) 3-ethyl (1R,3S,5R)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate;O2-tert-butyl O3-ethyl (1R,3S,5R)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate;2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester, (1R,3S,5R)-
CBNumber:
CB53133872
Molecular Formula:
C13H21NO4
Molecular Weight:
255.31
MOL File:
214193-10-9.mol

N-Boc-L-trans-4,5-methanoproline ethyl ester Chemical Properties,Uses,Production

Uses

N-Boc-L-trans-4,5-methanoproline Ethyl Ester is an impurity of the drug Saxagliptin (S143500), a potent and selective reversible inhibitor of dipeptidyl peptidase-4.

N-Boc-L-trans-4,5-methanoproline ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester, (1R,3S,5R)- Saxagliptin Impurity 47 O2-tert-butyl O3-ethyl (1R,3S,5R)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate 2-(tert-Butyl) 3-ethyl (1R,3S,5R)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate Ethyl (1R,3S,5R)-N-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylate N-Boc-L-trans-4,5-methanoproline Ethyl Ester 214193-10-9