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N-Stearoyl-phytosphingosine

N-Stearoyl-phytosphingosine Structure
CAS No.
34354-88-6
Chemical Name:
N-Stearoyl-phytosphingosine
Synonyms
DS-CeraMide Y3S;C18-PHYTOCERAMIDE;Phytoceramide III;N-STEAROYL-PHYTOSPHINGOSINE;YEAST N-18:0 PHYTOSPHINGOSINE;C18 3-Hydroxy DihydroceraMide;C18 Phytoceramide (t18:0/18:0);2S,3S,4R-2-StearoylaMide-1,3,4-octadecanetriol;D-ribo-1,3,4-Trihydroxy-2-octadecanoylaMidooctadecane;N-STEAROYL-PHYTOSPHINGOSINE (SACCHAROMYCES CEREVISIAE)
CBNumber:
CB5342684
Molecular Formula:
C36H73NO4
Molecular Weight:
583.97
MOL File:
Mol file
Modify Date:
2024/4/5 16:00:29

N-Stearoyl-phytosphingosine Properties

Melting point 122-124°C
Boiling point 718℃ at 10hPa
Density 0.994-1.014 at 20℃
vapor pressure 0Pa at 25℃
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform : Methanol = 3 : 1 (Slightly), Pyridine (Slightly, Heated, Sonicated)
form Solid
color White to Off-White
InChIKey IEZRNEGTKRQRFV-LFBNJJMOSA-N
SMILES C(N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC)(=O)CCCCCCCCCCCCCCCCC
LogP 12.01 at 25℃ and pH7

N-Stearoyl-phytosphingosine Chemical Properties,Uses,Production

Description

N-Stearoyl-phytosphingosine (SPS), sphingolipids frequently found in mammalian skin, plants, and yeast, have been used in cosmetics. In mice, treatment with SPS inhibited histamine-induced scratching behavior and vascular permeability. This agent inhibited the expression of the allergic cytokines IL-4 and TNF-a and the activation of the transcription factors NF-jB and c-jun in histamine-stimulated skin tissues[1].

Uses

An intercellular lipid that benefits skin hydration and protects against SLS irritation.

References

[1] Kwon-Ryeol Ryu. “Anti-scratching Behavioral Effects of N-Stearoyl-phytosphingosine and 4-Hydroxysphinganine in Mice.” Lipids 45 7 (2010): 613–618.

N-Stearoyl-phytosphingosine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Stearoyl-phytosphingosine Suppliers

Global( 37)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Chongqing Zhihe Biopharmaceutical Co., Ltd. +86-18580541567 +86-17782035140 China 301 58 Inquiry
BINBO BIOLOGICAL CO.,LTD +8618629063126 China 346 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
Zhengzhou Lingzhiyue Technology Co., Ltd +86-0371-55074660 +86-13783527580 China 3152 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
CONTIDE BIOTECH CO.,LTD +852-53358525 China 568 58 Inquiry
LGC Standards +44 (0)20 8943 8480 United Kingdom 6495 0 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Shandong Juntai Pharmaceutical Co. LTD 18615688519 18615688519 China 159 58 Inquiry

34354-88-6(N-Stearoyl-phytosphingosine)Related Search:

YEAST N-18:0 PHYTOSPHINGOSINE N-STEAROYL-PHYTOSPHINGOSINE N-STEAROYL-PHYTOSPHINGOSINE (SACCHAROMYCES CEREVISIAE) C18-PHYTOCERAMIDE (2S, 3S, 4R)-2-STEAROYLIMINO-1,3,4-OCTADECANETRIOL-1-PHOSPHOCHOLINE (SACCHAROMYCES CEREVISIAE) 2S,3S,4R-2-StearoylaMide-1,3,4-octadecanetriol C18 3-Hydroxy DihydroceraMide D-ribo-1,3,4-Trihydroxy-2-octadecanoylaMidooctadecane DS-CeraMide Y3S N-[(1S,2S,3R)-2,3-Dihydroxy-1-(hydroxyMethyl)heptadecyl]octadecanaMide C18 Phytoceramide (t18:0/18:0) Octadecanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]- Phytoceramide III 34354-88-6 C36H73NO4 Amines Fatty Acid Derivatives & Lipids Glycerols Intermediates & Fine Chemicals Pharmaceuticals