L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE
- CAS No.
- 159190-45-1
- Chemical Name:
- L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE
- Synonyms
- L-NIL HCL;L-NIL DIHYDROCHLORIDE;L-N6-(1-Iminoethyl)lysine;OQIBCXRAFAHXMM-KLXURFKVSA-N;L-N6-(1-IMINOETHYL)-LYSINE 2HCL;L-N6-(1-IMINOETHYL)LYSINE, DIHCL;L-Lysine ω-acetamidine dihydrochloride;L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE;LNIL dihydrochloride,L NIL dihydrochloride;N6-(1-IMINOETHYL)-L-LYSINE DIHYDROCHLORIDE
- CBNumber:
- CB5353543
- Molecular Formula:
- C8H18ClN3O2
- Molecular Weight:
- 223.7
- MOL File:
- 159190-45-1.mol
- Modify Date:
- 2023/6/8 9:03:06
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE Chemical Properties,Uses,Production
Description
L-NIL is a relatively selective inhibitor of iNOS. It exhibits IC50 values of 0.4-3.3 μM for iNOS as opposed to 8-38 and 17-92 μM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.
Uses
L-N6-(1-Iminoethyl)lysine dihydrochloride has been used as an inducible nitric oxide synthase (iNOS) inhibitor:
- to study its effects on leptin-induced modulation of fibronectin type III domain-containing five (FNDC5)/irisin in myocytes and fat cells of murine
- to study its effects on leptin-induced inflammation in hepatocytes
- to block the production of nitric oxide in mice bone marrow mesenchymal stromal cells (BMSCs)
Biochem/physiol Actions
Selective inhibitor of inducible nitric oxide synthase (iNOS).
L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE Suppliers
Global( 25)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25013 | 65 | Inquiry |
| Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9707 | 58 | Inquiry |
| Sigma-Aldrich | 021-61415566 800-8193336 | China | 51471 | 80 | Inquiry |
| Kanto Chemical Co., Inc. | +81 3 3663 7631 | Japan | 6762 | 74 | Inquiry |
| Wako Pure Chemical Industries, Ltd. | +81 6 6203 3741 | Japan | 6828 | 80 | Inquiry |
| Alexis Corporation | +41 61 926 8989 | Switzerland | 3599 | 74 | Inquiry |
| EMD Biosciences, Inc. | 858 450 5500 | United States | 6529 | 66 | Inquiry |
159190-45-1(L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE)Related Search:
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L-NIL HCL
L-N6-(1-IMINOETHYL)-LYSINE 2HCL
L-N6-(1-IMINOETHYL)LYSINE, DIHCL
L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE
N6-(1-IMINOETHYL)-L-LYSINE DIHYDROCHLORIDE
L-Lysine, N6-(1-iMinoethyl)-, (Hydrochloride) (1:2)
L-Lysine ω-acetamidine dihydrochloride
L-NIL DIHYDROCHLORIDE
OQIBCXRAFAHXMM-KLXURFKVSA-N
L-N6-(1-Iminoethyl)lysine
LNIL dihydrochloride,L NIL dihydrochloride
159190-45-1
Nitric Oxide Synthase
Enzyme Inhibitors
Enzyme Inhibitors by Enzyme
Enzymes, Inhibitors, and Substrates
L to O
BioChemical
Biochemicals and Reagents
Nitric Oxide