2',7'-DIFLUOROFLUORESCEIN

2',7'-DIFLUOROFLUORESCEIN Structure
CAS No.
195136-58-4
Chemical Name:
2',7'-DIFLUOROFLUORESCEIN
Synonyms
OREGON GREEN(TM) 488;2',7'-DIFLUOROFLUORESCEIN;2',7'-Difluorofluorescein;2',7'-Difluoro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;2',7'-Difluoro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;2',7'-Difluoro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-difluoro-3',6'-dihydroxy-
CBNumber:
CB5361380
Molecular Formula:
C20H10F2O5
Molecular Weight:
368.29
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2023/6/8 9:03:05

2',7'-DIFLUOROFLUORESCEIN Properties

Boiling point 591.7±50.0 °C(Predicted)
Density 1.70±0.1 g/cm3(Predicted)
solubility Insoluble in water; soluble in N,Ndimethylformamide
form A solid
pka 4.8, (at 22℃);4.7, (at 22℃)
color Orange powder
λmax 490 nm (Buffer pH 9.0)
Major Application As geothermal tracers;TiO2 nanoparticles for light energy conversion
Biological Applications Detecting atherosclerosis;detecting/monitoring amyloid Aβ production/accumulation/aggregation/disaggregation; diagnosing Alzheimer’s disease;estimating/measuring concentration of cortisol, melatonin, secretory IgA in body fluids;11 evaluating cetuximab-based imaging probe to target epidermal growth factor receptor (EGFR);examining biodistribution of proteins;investigating/measuring protein-protein and protein-nucleic acid interactions;measuring pH of apoplast at the root surface;visualizing hair follicles;as a substrate for measuring β-lactamase activity,phosphatases activity

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
NFPA 704
0
2 0

2',7'-DIFLUOROFLUORESCEIN Chemical Properties,Uses,Production

Uses

2'',7''-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases.

2',7'-DIFLUOROFLUORESCEIN Preparation Products And Raw materials

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OREGON GREEN(TM) 488 2',7'-DIFLUOROFLUORESCEIN 2',7'-Difluoro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 2',7'-Difluoro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-difluoro-3',6'-dihydroxy- 2',7'-Difluorofluorescein 2',7'-Difluoro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 195136-58-4 C20H10F2O5