GLY-ARG-GLY-ASP-SER

GLY-ARG-GLY-ASP-SER Structure
CAS No.
96426-21-0
Chemical Name:
GLY-ARG-GLY-ASP-SER
Synonyms
GRGDS;GRGDS 1/2ACOH 2H2O;GLY-ARG-GLY-ASP-SER;H-GLY-ARG-GLY-ASP-SER-OH;Gly-Arg-Gly-Asp-Ser (TFA);GRGDS, fibrinogen fragment;GLY-ARG-GLY-ASP-SER ACETATE;GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O;Gly-Arg-Gly-Asp-Ser >=97% (HPLC);H-Gly-Arg-Gly-Asp-Ser-OH TFA salt
CBNumber:
CB5414527
Molecular Formula:
C17H30N8O9
Molecular Weight:
490.47
MOL File:
96426-21-0.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:11

GLY-ARG-GLY-ASP-SER Properties

Density 1.66±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO : 100 mg/mL (203.89 mM);Water : 33.33 mg/mL (67.96 mM)
pka 2.85±0.10(Predicted)
form White to off-white lyophilized solid
color White to off-white
Sequence H-Gly-Arg-Gly-Asp-Ser-OH

SAFETY

Risk and Safety Statements

WGK Germany  3

GLY-ARG-GLY-ASP-SER price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G4391 Gly-Arg-Gly-Asp-Ser ≥97% (HPLC) 96426-21-0 1MG ₹6884.7 2022-06-14 Buy
Sigma-Aldrich(India) G4391 Gly-Arg-Gly-Asp-Ser ≥97% (HPLC) 96426-21-0 5MG ₹22775.8 2022-06-14 Buy
Product number Packaging Price Buy
G4391 1MG ₹6884.7 Buy
G4391 5MG ₹22775.8 Buy

GLY-ARG-GLY-ASP-SER Chemical Properties,Uses,Production

Uses

Gly-Arg-Gly-Asp-Ser has been used-

  • as an antigen to determine whether integrin α4 or α5 hinders the adhesion of day 3 postirradiation thymocytes to thymic epithelial cells, in mice
  • for the treatment of collagen IV-coated dishes to study the role of integrins α1, αv, β1, and β3 in Sca-1+ progenitor cell differentiation into SMCs (smooth muscle cells)
  • as a blocking peptide for the pre-incubation of Nisseria meningitides strains, to perform blocking experiments to study the interactions between these bacterial strains and fibronectin
  • for the pre-treatment of EL-4 cells infected by AdCMV-GFP (cytomegalovirus-green fluorescent protein), to study whether interaction with cellular integrins is essential for the transduction of adenovirus

General Description

Gly-Arg-Gly-Asp-Ser peptide sequence is identical to the cell-binding region of fibronectin protein. Arg-Gly-Asp (RGD) region is found in various proteins, and is crucial for facilitating cell-adhesive activity.

Biochem/physiol Actions

Antagonist of integrin function

GLY-ARG-GLY-ASP-SER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 118)Suppliers
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Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
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Hebei Miaoyin Technology Co.,Ltd +86-17367732028 +86-17367732028 China 3581 58 Inquiry
Nanjing TGpeptide +86-13347807150 +86-13347807150 China 3279 58 Inquiry
Zhejiang Hangyu API Co., Ltd +8617531972939 China 2944 58 Inquiry
GRGDS 1/2ACOH 2H2O GRGDS, FIBRONECTIN ATTACHMENT PEPTIDE GLY-ARG-GLY-ASP-SER GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O H-GLY-ARG-GLY-ASP-SER-OH L-Serine, N-(N-(N-(N2-glycyl-L-arginyl)glycyl)-L-alpha-aspartyl)- glycyl-arginyl-glycyl-aspartyl-serine GLY-ARG-GLY-ASP-SER ACETATE L-Serine, glycyl-L-arginylglycyl-L-a-aspartyl- (6S,12S,15S)-1-aMino-6-(2-aMinoacetaMido)-12-(carboxyMethyl)-15-(hydroxyMethyl)-1-iMino-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid GRGDS, fibrinogen fragment Glycyl-L-Arginylglycyl-L-alpha-Aspartyl-L-Serine H-Gly-Arg-Gly-Asp-Ser-OH - CAS 96426-21-0 - Calbiochem (S)-3-{2-[(S)-2-(2-Amino-acetylamino)-5-guanidino-pentanoylamino]-acetylamino}-N-((S)-1-carboxy-2-hydroxy-ethyl)-succinamic acid Gly-Arg-Gly-Asp-Ser (TFA) L-Serine, glycyl-L-arginylglycyl-L-α-aspartyl- Gly-Arg-Gly-Asp-Ser >=97% (HPLC) H-Gly-Arg-Gly-Asp-Ser-OH TFA salt Glycyl-L-arginylglycyl-L-α-aspartyl-L-serine GRGDS 96426-21-0 Extracellular Matrix Peptides and Proteins Extracellular Matrix Cytoskeleton and Extracellular Matrix Cell Biology Cell Signaling and Neuroscience BioChemical Cell Signaling Enzymes ECM Related Proteins and PeptidesCytoskeleton and Extracellular Matrix Extracellular Matrix Extracellular Matrix Peptides (ECM) Extracellular Matrix Peptides and ProteinsPeptides for Cell Biology Fibronectin Fragments and Analogs Matrix Metalloproteinases Products peptide