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6-Methylthioguanine

6-Methylthioguanine Structure
CAS No.
1198-47-6
Chemical Name:
6-Methylthioguanine
Synonyms
NSC 29420;TIMTEC-BB SBB000228;6-Methylthioguanine;S-Methyl-6-thioguanine;S6-Methyl-6-thioguanine;2-Amino-6-methylthiopurine;Mercaptopurine Impurity 29;6-Methylthioguanine USP/EP/BP;2-AMINO-6-METHYLMERCAPTOPURINE;6-Methylthio-7H-purine-2-amine
CBNumber:
CB5468494
Molecular Formula:
C6H7N5S
Molecular Weight:
181.22
MOL File:
1198-47-6.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:32

6-Methylthioguanine Properties

Melting point 235.5°C
Density 1.403 (estimate)
refractive index 1.4606 (estimate)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  24/25-39-26
WGK Germany  3
HS Code  29335995
NFPA 704
1
2 0

6-Methylthioguanine price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A9546 2-Amino-6-methylmercaptopurine ≥95% 1198-47-6 100MG ₹9493.53 2022-06-14 Buy
Product number Packaging Price Buy
A9546 100MG ₹9493.53 Buy

6-Methylthioguanine Chemical Properties,Uses,Production

Chemical Properties

off-white crystalline powder

Uses

As a metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine, 6-Methylthioguanine can be used as an effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.

Biochem/physiol Actions

2-Amino-6-methylmercaptopurine is synthesized from 6-mercaptopurine by the S methylation activity of thiopurine methyl transferase (TMPT) enzyme.

6-Methylthioguanine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 66)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
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Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
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Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 China 9242 58 Inquiry
1H-Purin-2-amine, 6-(methylthio)- 2-Amino-6-methylthiopurine 6-(Methylsulfanyl)-1H-purin-2-amine 6-Methylthioguanine TIMTEC-BB SBB000228 6-(METHYLSULFANYL)-7H-PURIN-2-YLAMINE 2-AMINO-6-METHYLMERCAPTOPURINE 2-AMINO-6-METHYLMERCAPTOPURINE 95% 2-Amino-6-(methylthio)-9H-purine 6-(Methylthio)-9H-purine-2-amine 6-Methylthio-7H-purine-2-amine 2-Amino-6-methylmercaptopurine,95% NSC 29420 S6-Methyl-6-thioguanine S-Methyl-6-thioguanine 6-(methylthio)-1H-purin-2-amine 2-Amino-6-methylmercaptopurine-[13C, d3] (Solution) 9H-Purin-2-amine, 6-(methylthio)- Mercaptopurine Impurity 29 6-Methylthioguanine USP/EP/BP 6-(methylsulfanyl)-7H-purin-2-amine 6-(Methylthio)-7H-purin-2-amine 1198-47-6 C6H7N5S Biochemicals and Reagents BioChemical Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Mutagenesis Research Chemicals, Sulfur & Selenium Compounds Bases & Related Reagents Heterocycles Metabolites & Impurities Mutagenesis Research Chemicals Nucleotides Sulfur & Selenium Compounds