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TELMISARTAN-D3

TELMISARTAN-D3 Structure
CAS No.
1189889-44-8
Chemical Name:
TELMISARTAN-D3
Synonyms
Pritor-d3;BIBR 277-d3;Micardis-d3;BIBR 277SE-d3;TELMISARTAN-D3;Telmisartan-d3 in methanol;4'-[(1,4'-DiMethyl-2'-propyl[2,6'-bi-H-benziMidazol]-1'-yl)Methyl][1,1'-biphenyl]-2-carboxylic Acid-d3;4'-[[4-Methyl-6-(1-Methyl-2-benziMidazolyl)-2-propyl-1-benziMidazolyl] Methyl]-2-biphenylcarboxylic Acid-d3;4'-({4-methyl-6-[1-(2H?)methyl-1H-1,3-benzodiazol-2-yl]-2-propyl-1H-1,3-benzodiazol-1-yl}methyl)-[1,1'-biphenyl]-2-carboxylic acid;Telmisartan D3Q: What is Telmisartan D3 Q: What is the CAS Number of Telmisartan D3 Q: What is the storage condition of Telmisartan D3 Q: What are the applications of Telmisartan D3
CBNumber:
CB5730269
Molecular Formula:
C33H27D3N4O2
Molecular Weight:
517.64
MOL File:
Mol file
Modify Date:
2024/11/19 20:33:22

TELMISARTAN-D3 Properties

Melting point 262-265°C
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
color White to Beige

TELMISARTAN-D3 Chemical Properties,Uses,Production

Description

Telmisartan-d3 is intended for use as an internal standard for the quantification of telmisartan by GC- or LC-MS. Telmisartan is a nonpeptide angiotensin (AT) II receptor antagonist which selectively and insurmountably inhibits the AT II receptor subtype AT1 (Ki = 3.7 nM). It also acts as a partial agonist of peroxisome proliferator-activated receptor gamma (PPARγ), activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (; EC50 = 4.5 μM). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.

Chemical Properties

Off-White Crystalline Solid

Uses

TelMisartan-d3 is an angiotensin II receptor antagonist.

TELMISARTAN-D3 Preparation Products And Raw materials

Raw materials

Preparation Products

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TELMISARTAN-D3 4'-[(1,4'-DiMethyl-2'-propyl[2,6'-bi-H-benziMidazol]-1'-yl)Methyl][1,1'-biphenyl]-2-carboxylic Acid-d3 4'-[[4-Methyl-6-(1-Methyl-2-benziMidazolyl)-2-propyl-1-benziMidazolyl] Methyl]-2-biphenylcarboxylic Acid-d3 BIBR 277-d3 BIBR 277SE-d3 Micardis-d3 Pritor-d3 Telmisartan D3Q: What is Telmisartan D3 Q: What is the CAS Number of Telmisartan D3 Q: What is the storage condition of Telmisartan D3 Q: What are the applications of Telmisartan D3 4'-({4-methyl-6-[1-(2H?)methyl-1H-1,3-benzodiazol-2-yl]-2-propyl-1H-1,3-benzodiazol-1-yl}methyl)-[1,1'-biphenyl]-2-carboxylic acid Telmisartan-d3 in methanol 1189889-44-8 C33H27D3N4O2 Intermediates & Fine Chemicals Metabolites Pharmaceuticals Various Metabolites and Impurities Aromatics Heterocycles Isotope Labelled Compounds