ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Amino alcohol derivative >3-Amino-1-adamantanol
3-Amino-1-adamantanol
- CAS No.
- 702-82-9
- Chemical Name:
- 3-Amino-1-adamantanol
- Synonyms
- 3-AMINO-1-ADAMANTANOL;3-AMINOADAMANTAN-1-OL;3-Amino-1-admantanol;4-aminoadamantan-1-ol;3-Amino-1-Adamantanamine;1-AMINO-3-HYDROXYADAMANTANE;3-Hydroxy-1-aminoadamantane;C1oH17NO;AKOS BB-9784;CHEMBRDG-BB 4003530
- CBNumber:
- CB5777891
- Molecular Formula:
- C10H17NO
- Molecular Weight:
- 167.25
- MOL File:
- 702-82-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | 265 °C (dec.)(lit.) |
|---|---|
| Boiling point | 266.8±23.0 °C(Predicted) |
| Density | 1.252±0.06 g/cm3(Predicted) |
| Flash point | 230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 15.07±0.40(Predicted) |
| form | Crystalline Powder |
| color | White to yellow |
| Water Solubility | Soluble in organic solvents,insoluble in water. |
| InChI | InChI=1S/C10H17NO/c11-9-2-7-1-8(3-9)5-10(12,4-7)6-9/h7-8,12H,1-6,11H2 |
| InChIKey | DWPIPTNBOVJYAD-UHFFFAOYSA-N |
| SMILES | C12(O)CC3CC(CC(N)(C3)C1)C2 |
| CAS DataBase Reference | 702-82-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29221990 | |||||||||
| NFPA 704 |
|
3-Amino-1-adamantanol price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 523690 | 3-Amino-1-adamantanol 96% | 702-82-9 | 1G | ₹12124 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 523690 | 3-Amino-1-adamantanol 96% | 702-82-9 | 5G | ₹39554.55 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A2079 | 3-Amino-1-adamantanol min. 98.0 % | 702-82-9 | 1G | ₹7000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A2079 | 3-Amino-1-adamantanol min. 98.0 % | 702-82-9 | 5G | ₹23000 | 2022-05-26 | Buy |
3-Amino-1-adamantanol Chemical Properties,Uses,Production
Description
3-Amino-1-adamantanol is an important adamantane drug intermediate mainly used in the synthesis of inhibitors with antihyperglycaemic properties for the preparation of Vildagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor used in the treatment of type 2 diabetes.
Chemical Properties
White solid
Uses
As reagent, 3-Amino-1-hydroxyadamantane can be used in the preparation of Vildagliptin.
Synthesis
A preparation method of 3-amino-1-adamantanol comprises the following steps: (1) adding amantadine or a salt thereof to sulfuric acid at 10-30 DEG C and adding a mixed acid dropwise to perform a nitration reaction to obtain a reaction liquid; (2) adding the reaction liquid to water and mixing the reaction liquid with water to obtain a mixed solution; (3) performing a hydroxylation reaction under the effect of alkaline to obtain the 3-amino-1-adamantanol. The preparation method employs the raw material, is easy to obtain, is simple in operations, is environmentally protective, is low in cost, and is high in yield, which is generally higher than 80%, maximally 90.1%.
3-Amino-1-adamantanol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 604)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TAGOOR LABORATORIES PVT LTD | +919700187008 | AndhraPradesh, India | 93 | 58 | Inquiry |
| MAISURIYA PHARMA SOLUTIONS | +91 9870085570 | Gujarat, India | 65 | 58 | Inquiry |
| RP Industries | +91-9700187008 +91-9700187008 | Gujarat, India | 58 | 58 | Inquiry |
| HEMA PHARMACEUTICALS PVT LTD | +91-9537936912 +91-9537936912 | Gujarat, India | 48 | 58 | Inquiry |
| Molkem Chemicals | +91-917228022464 +91-7228022464 | Ahmedabad, India | 138 | 58 | Inquiry |
| MANVI BIOPHARMA PVT LTD, | +91-9951015911 +91-9951015911 | Hyderabad, India | 86 | 58 | Inquiry |
| SRINIVASA LABS | +91-8247888505 +91-8247888505 | Hyderabad, India | 76 | 58 | Inquiry |
| TRC FINE CHEMS | +91-7400278327 +91-8097105248 | Mumbai, India | 73 | 58 | Inquiry |
| SPC LIFESCIENCES PVT. LTD | +91-91-265-2658894 +91-9998016172 | Gujarat, India | 48 | 58 | Inquiry |
| Bhausa Life Sciences | +91-8154986830 +91-8154986830 | Gujarat, India | 201 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| TAGOOR LABORATORIES PVT LTD | 58 |
| MAISURIYA PHARMA SOLUTIONS | 58 |
| RP Industries | 58 |
| HEMA PHARMACEUTICALS PVT LTD | 58 |
| Molkem Chemicals | 58 |
| MANVI BIOPHARMA PVT LTD, | 58 |
| SRINIVASA LABS | 58 |
| TRC FINE CHEMS | 58 |
| SPC LIFESCIENCES PVT. LTD | 58 |
| Bhausa Life Sciences | 58 |
702-82-9(3-Amino-1-adamantanol)Related Search:
Amantadine
PotassiuM sodiuM Dehydroandrographolide Succinate
1-Adamantanol
3-Amino-1-propanesulfonic acid
3-Amino-1,2-propanediol
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1of4
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CHEMBRDG-BB 4003530
3-Amino-1-hydroxyadamantane
AKOS BB-9784
1-AMINO-3-ADAMANTANOL
TRICYCLO[3.3.1.13,7]DECAN-1-OL, 3-AMINO-
(5r,7s)-3-aminoadamantan-1-ol
3-Amino-1-adamantanol Hydrate
3-aminoadamantan-1-ol(SALTDATA: HCl)
Vildagliptin Intermediate 1
1-AMino adaMantane-3-ol
3-AMino-1-adaMantanole 3
(3-HydroxyadaMantan-1-yl)aMine
3-AMino-tricyclo[3.3.1.13,7]decan-1-ol
3-AMino-1-adaMantanol, 98+%
3-Aminoadamantan-1-ol, 3-Aminotricyclo[3.3.1.1~3,7~]decan-1-ol, 3-Hydroxytricyclo[3.3.1.1~3,7~]decan-1-amine
3-AMino-1-HydroxyadaMantane SynonyMs: 3-AMinoadaMantan-1-ol
3-AMino-1-adaMantano, 98%
3 - aMino adaMantane alcohol
3-Amino-1-hydroxyadamantane 3-Aminoadamantan-1-ol
3-Amino-1-adamantanol 3-Amino-1-adamantanol
3-aminoadamantan-1-ol hydrochloride
Vigliptin impurity 15
Vildagliptin Amino Alcohol Impurity
Vildagliptin Impurity 24
3-Amino-1-hydroxyadamantane
(Vildagliptin)
3-Amino-1-adamantanol Hydrate>
3-amino-1-amantadine
3-Amino-1-hydroxyadamantane USP/EP/BP
Vildagliptin Impurity 74
Vildagliptin VLN-01(3-Hydroxy-1-adamantan amine)
Vildagliptin Amino Alcohol Impurity/Vildagliptin Impurity 15
Vildagliptin Amino Alcohol ImpurityQ: What is
Vildagliptin Amino Alcohol Impurity Q: What is the CAS Number of
Vildagliptin Amino Alcohol Impurity Q: What is the storage condition of
Vildagliptin Amino Alcohol Impurity Q: What are the applications of
Vildagliptin Amino Alcohol Impurity
3-AMINO-1-ADAMANTANOL
3-AMINOADAMANTAN-1-OL
1-AMINO-3-HYDROXYADAMANTANE
3-Hydroxy-1-aminoadamantane
4-aminoadamantan-1-ol
3-Amino-1-admantanol
3-Amino-1-Adamantanamine
3-AMINO-1-ADAMNANOL
3-Amino -1-Adamantol
2-Amino-1-Hydroxyadamantane
3-amino-1-hydroxy Ademantane
1-Amino-3- Admatanol
C1oH17NO
3-Amino-1-Adamentanol
Vildagliptin Amino Alcohol Impurity
1-Amino-3-adamantanol
702-82-9
02-82-9
702-82-7
702-89-2
C10H18NO
C10H17NOxH2O
C10H17NOH2O
Building Blocks
Amino Alcohols
Organic Building Blocks
Oxygen Compounds