Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Structure
CAS No.
85267-60-3
Chemical Name:
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate
Synonyms
3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine;Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate
CBNumber:
CB59007160
Molecular Formula:
C18H24N2O7Si
Molecular Weight:
408.48
MOL File:
85267-60-3.mol
Modify Date:
2023/4/27 16:27:43

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Properties

Density 1.27±0.1 g/cm3(Predicted)
pka 8.83±0.10(Predicted)

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Chemical Properties,Uses,Production

Uses

3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

1.jpg
1.Add DMAP (0.16 mmol, 20 mg) to a stirred suspension of 2'-deoxyuridine (1 mmol, 228 mg) in acetic anhydride (7.5 mL).2.Observe the reaction mixture become homogenous for 6 hours.3.Remove the volatiles in vacuum.4.Purify the residue by flash chromatography on silica gel eluted with EA/cyclohexane (4:1 → 19:1, v/v) to obtain 3',5'-di-O-acetyl-2'-deoxyuridine.

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Preparation Products And Raw materials

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Suppliers

Global( 2)Suppliers
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Zhengzhou Chemprize Biotech Co., Ltd. 15981919713 China 408 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +86-15658003402 China 347 58 Inquiry
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate 3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine 85267-60-3 C18H24N2O7Si