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segetalin B

segetalin B Structure
CAS No.
164991-89-3
Chemical Name:
segetalin B
Synonyms
segetalin B;Cyclo（AGAVW）;product/154129;Cyclo(L-alanylglycyl-L-valyl-L-alanyl-L-tryptophyl);(3S,6S,9S,12S)-6-((1H-Indol-3-yl)methyl)-12-isopropyl-3,9-dimethyl-1,4,7,10,13-pentaazacyclopentadecane-2,5,8,11,14-pentaone
CBNumber:
CB61376966
Molecular Formula:
C24H32N6O5
Molecular Weight:
484.55
MOL File:
164991-89-3.mol
Modify Date:
2024/7/2 8:55:12
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segetalin B Properties

Boiling point 999.4±65.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
solubility DMSO : 250 mg/mL (515.94 mM; Need ultrasonic)
pka 13.35±0.70(Predicted)
form Solid
color White to off-white

segetalin B Chemical Properties,Uses,Production

Description

Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity.

Physical properties

Cyclic pentapeptide. Constit. of the seeds of Vaccaria segetalis (Caryophyllaceae).Needles.Mp 153-155°C.

Pharmacology

Examples of naturally occurring bioactive cyclopeptides are Segetalins A and B，which were isolated from Vaccaria segetalis (Caryophyllacea) and were shown to have estrogen-like activity. The seeds of Vaccaria segetalis are used in Chinese folk medicine to activate blood flow, to promote milk secretion, and to treat amenorrhea and breast infections. That Segetalin A and Segetalin B have the Try-Ala-Gly-Val (WAGV) sequence in common indicates this is the biologically active part of the molecules. NMR studies indicate,however,that the orientation of the Val residue is different in the molecules.The effect of this amino acid on the activity of the compounds might not be very important.

segetalin B Preparation Products And Raw materials

Raw materials

Preparation Products

segetalin B Suppliers

Global( 89)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10312 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Zhejiang Hangyu API Co., Ltd +8617531972939 China 2944 58 Inquiry
Shanghai HongTide Biotechnology Co.,Ltd. 19961912513 China 4679 58 Inquiry
Shanghai Taopu Industrial Co., LTD 18018507602 15900573766 China 3031 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 China 6210 58 Inquiry
Wuhan Huangzhen Biochemical Co., Ltd 13795480948 13795480948 China 4958 58 Inquiry
Hangzhou Beiputai Biopharmaceutical Co., Ltd 0571-85350119 13305819357 China 3849 58 Inquiry
Supplier Advantage
Chengdu GLP biotechnology Co Ltd 58
Shenzhen Nexconn Pharmatechs Ltd 58
Chengdu Biopurify Phytochemicals Ltd. 58
TargetMol Chemicals Inc. 58
Zhejiang Hangyu API Co., Ltd 58
Shanghai HongTide Biotechnology Co.,Ltd. 58
Shanghai Taopu Industrial Co., LTD 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
Wuhan Huangzhen Biochemical Co., Ltd 58
Hangzhou Beiputai Biopharmaceutical Co., Ltd 58

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segetalin B product/154129 Cyclo(L-alanylglycyl-L-valyl-L-alanyl-L-tryptophyl) Cyclo（AGAVW） (3S,6S,9S,12S)-6-((1H-Indol-3-yl)methyl)-12-isopropyl-3,9-dimethyl-1,4,7,10,13-pentaazacyclopentadecane-2,5,8,11,14-pentaone 164991-89-3 64991-89-3 C24H32N6O5 Cyclic peptides