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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Structure
CAS No.
135270-07-4
Chemical Name:
1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
Synonyms
Efinaconazole Impurity 18;Efinaconazole Related Impurity 4;(1H-1,2,4-triazol-1-yl)methyl>(2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-<(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol...;(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane;1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole;1H-1,2,4-Triazole, 1-[[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI);1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
CBNumber:
CB62705242
Molecular Formula:
C12H11F2N3O
Molecular Weight:
251.23
MOL File:
135270-07-4.mol
MSDS File:
SDS
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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Properties

Boiling point 371.6±52.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
pka 2.75±0.10(Predicted)

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Chemical Properties,Uses,Production

Uses

(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of ent-Efinaconazole (E435075); the S,S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Preparation Products And Raw materials

Raw materials

Preparation Products

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Suppliers

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ANHUI WITOP BIOTECH CO., LTD 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
China National Standard Pharmaceutical Corporation Limited 58
Guangzhou Tosun Pharmaceutical Limited 58

135270-07-4(1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole)Related Search:

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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Efinaconazole Related Impurity 4 (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane (1H-1,2,4-triazol-1-yl)methyl> (2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-< Efinaconazole Impurity 18 1H-1,2,4-Triazole, 1-[[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI) (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol... 1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity) 135270-07-4