(6R)-Hydroxy (S,S)-Palonosetron

(6R)-Hydroxy (S,S)-Palonosetron Structure
CAS No.
176019-33-3
Chemical Name:
(6R)-Hydroxy (S,S)-Palonosetron
Synonyms
Aurofusarin Impurity 14;Palonosetron Impurity 28;Palonosetron Impurity 47;(6R)-Hydroxy Palonosetron;(6R)-Hydroxy (S,S)-Palonosetron;(3aS,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-, [3aS-[2(R*),3aα,6β]]- (9CI)
CBNumber:
CB62709912
Molecular Formula:
C19H24N2O2
Molecular Weight:
312.41
MOL File:
176019-33-3.mol

(6R)-Hydroxy (S,S)-Palonosetron Properties

Boiling point 515.4±50.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
pka 14.32±0.20(Predicted)

(6R)-Hydroxy (S,S)-Palonosetron Chemical Properties,Uses,Production

Uses

(6R)-Hydroxy (S,S)-Palonosetron is a stereoisomer of (6S)-Hydroxy (S,S)-Palonosetron (H949365). (6S)-Hydroxy (S,S)-Palonosetron (H949365) is a metabolite of Palonosetron (P165800, HCl salt) which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting.

(6R)-Hydroxy (S,S)-Palonosetron Preparation Products And Raw materials

Raw materials

Preparation Products

(6R)-Hydroxy (S,S)-Palonosetron Suppliers

(6R)-Hydroxy (S,S)-Palonosetron (3aS,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one (6R)-Hydroxy Palonosetron 1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-, [3aS-[2(R*),3aα,6β]]- (9CI) Palonosetron Impurity 47 Aurofusarin Impurity 14 Palonosetron Impurity 28 176019-33-3