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(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one

(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one Structure
CAS No.
953805-20-4
Chemical Name:
(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one
Synonyms
(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one;3-{4-[2-(4-fluorophenyl)-5,5-dimethyl-[1,3]dioxin-2-yl]butyryl}(4S)-phenyl-1,3-oxazolidin-2-one;2-Oxazolidinone, 3-[4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-, (4S)-
CBNumber:
CB62735625
Molecular Formula:
C25H28FNO5
Molecular Weight:
441.49
MOL File:
953805-20-4.mol
Modify Date:
2023/5/15 10:43:57
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(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one Properties

Boiling point 583.3±50.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
solubility soluble in DCM, Ethyl Acetate
form Solid
pka -3.09±0.40(Predicted)
color White or Yellow

(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one Chemical Properties,Uses,Production

Uses

(4S)-3-[4-[2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of (3’R,3R,4R)-Ezetimibe (E974990), a structural analog of Ezetimibe (E975000). Ezetimibe is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.

(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one Preparation Products And Raw materials

Raw materials

(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone neopentyl glycol

Preparation Products

(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one Suppliers

Global( 8)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd 18072846723; 18072846723 China 18867 58 Inquiry
Nanjing Becas pharmatech Ltd. 13912903754 China 2377 58 Inquiry
AstaTech, Inc (215) 785 3197 United States 6379 58 Inquiry
Shanghai Mayzem Pharmtech Co., Ltd. 18501708306 China 520 56 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 13675144456 China 11442 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd 58
Nanjing Becas pharmatech Ltd. 58
AstaTech, Inc 58
Shanghai Mayzem Pharmtech Co., Ltd. 56
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
(S)-3-(4-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one 3-{4-[2-(4-fluorophenyl)-5,5-dimethyl-[1,3]dioxin-2-yl]butyryl}(4S)-phenyl-1,3-oxazolidin-2-one 2-Oxazolidinone, 3-[4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-, (4S)- 953805-20-4 C25H28FNO5