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N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Structure
CAS No.
1438071-12-5
Chemical Name:
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
Synonyms
GSK-2945;GSK-2945 (GSK2945 );GSK 2945 DISCONTINUED. Please see G797405;2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro-;N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
CBNumber:
CB63464337
Molecular Formula:
C20H18Cl2N2O2S
Molecular Weight:
421.34
MOL File:
1438071-12-5.mol
Modify Date:
2024/10/23 13:36:13
Request For Quotation

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Properties

Boiling point 525.0±45.0 °C(Predicted)
Density 1.363±0.06 g/cm3(Predicted)
solubility Acetonitrile (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
pka 5.23±0.50(Predicted)
form Solid
color Off-White to Light Beige
Stability Hygroscopic

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Chemical Properties,Uses,Production

Uses

GSK 2945 is an antagonist with high specificity for REV-ERBα, Nuclear heme receptor reverse erythroblastosis virus, which is known to regulate circadian rhythm and more specifically, regulation of cholesterol 7α-hydroxylase (CYP7A1) and bile acid synthesis.

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Preparation Products And Raw materials

Raw materials

4-CHLORO-2-METHYLBENZALDEHYDE 4-Chlorobenzylamine

Preparation Products

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Suppliers

Global( 9)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32080 58 Inquiry
TargetMol Chemicals Inc. United States 38470 58 Inquiry
TargetMol Chemicals Inc. +8613564774135 United States 19863 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9272 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24647 58 Inquiry
ShangHai Movin Pharmaceutical Co., Ltd. 13681854265 China 508 55 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; China 29774 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
ShangHai Movin Pharmaceutical Co., Ltd. 55
MedChemExpress 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine GSK-2945 GSK-2945 (GSK2945 ) 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro- GSK 2945 DISCONTINUED. Please see G797405 1438071-12-5