(R)-N-Boc-3-pyrrolidineacetic acid

CAS No.: 204688-60-8

Chemical Name:: (R)-N-Boc-3-pyrrolidineacetic acid

Synonyms: (R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid;(R)-1-Boc-3-pyrrolidineacetic acid;(R)-N-BOC-3-PYRROLIDINEACETIC ACID;N-BOC-(R)-pyrrolidin-3-acetic acid;(3R)-1-Boc-3-pyrrolidineacetic acid;(R)-N-BOC-PYRROLIDINE-3-ACETIC ACID;(R)-1-N-Boc-3-pyrrolidineacetic acid;(R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid;(R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID;(R)-N-Boc-3-(R)-(1-Boc-Pyrrolidin-3-yl)-aceticacid

CBNumber:: CB6409081

Molecular Formula:: C11H19NO4

Molecular Weight:: 229.27

MOL File:: 204688-60-8.mol

MSDS File:: SDS

Modify Date:: 2024/5/15 10:03:47

Request For Quotation

(R)-N-Boc-3-pyrrolidineacetic acid Properties

Boiling point	357.4±15.0 °C(Predicted)
Density	1.151±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	4.65±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard Codes	T,N
Risk Statements	25-50
Safety Statements	45-61
RIDADR	UN2811
HS Code	2933998090

(R)-N-Boc-3-pyrrolidineacetic acid Chemical Properties,Uses,Production

Synthesis

(R)-N-Boc-3-pyrrolidineacetic acid is synthesised using Di-tert-butyl dicarbonate as raw material by chemical reaction. The specific synthesis steps are as follows:
A solution of 4.95 g of the preceding step product in 50 ml of dichloromethane and 25 ml of trifluoroacetic acid is stirred at room temperature for 3 h. and concentrated. The residue is dissolved in 40 ml of dioxan and 40 ml of 1N NaOH, treated at room temperature with 4.3 g of di-tert-butyl dicarbonate in 40 ml of dioxan and stirred for 1.5 h. The reaction mixture is diluted with ether, the organic phase is washed with 1N NaOH and the aqueous phase is acidified with 3N HCl. Extraction of the aqueous phase with ether, washing, drying and concentration of the ether phase gives 0.72 g of tert-butyl(R)-3-carboxymethyl-pyrrolidine-1-carboxylate.
(R)-N-Boc-3-pyrrolidineacetic acid synthesis

(R)-N-Boc-3-pyrrolidineacetic acid Preparation Products And Raw materials

Raw materials

(R)-diethyl 2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)malonate tert-Butyl (3S)-3-({[(4-methylbenzene)sulfonyl]oxy}methyl)pyrrolidine-1-carboxylate (R)-2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)Malonic acid (S)-3-CYANOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-3-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(R)-3-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER ethyl 2-chloro-4-ethoxy-nicotinate Di-tert-butyl dicarbonate

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Preparation Products

(R)-ethyl 2-(pyrrolidin-3-yl)acetate hydrochloride

(R)-N-Boc-3-pyrrolidineacetic acid Suppliers

Global( 118)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	China	7287	58	Inquiry
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	China	2169	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	CHINA	21149	58	Inquiry
WinWin Chemical CO., Limited	+86-0577-64498589 +8615325081899	China	14198	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	China	52861	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Jinan Carbotang Biotech Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
WinWin Chemical CO., Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58

(R)-N-Boc-3-pyrrolidineacetic acid Spectrum

(R)-N-Boc-3-pyrrolidineacetic acid(204688-60-8)¹HNMR

204688-60-8((R)-N-Boc-3-pyrrolidineacetic acid)Related Search:

Ethyl acetate tert-Butyl carbazate Pyrrolidine Folic acid Acetic acid

Citric acid Trifluoroacetic acid Allyl phenoxyacetate Ethyl 2-(Chlorosulfonyl)acetate Fluroxypyr

Stearic acid Trichloroacetic acid Phenoxyacetic acid N-Carbobenzyloxyglycine Ascoric Acid

Acetic anhydride Peroxyacetic acid Chloroacetic acid

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(R)-1-Boc-3-pyrrolidineacetic acid (R)-N-Boc-3-(R)-(1-Boc-Pyrrolidin-3-yl)-aceticacid 2-[(3R)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]acetic acid (R)-3-CARBOXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID (R)-N-BOC-PYRROLIDINE-3-ACETIC ACID (R)-N-BOC-3-PYRROLIDINEACETIC ACID (R)-1-N-Boc-3-pyrrolidineacetic acid (R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid (3R)-1-Boc-3-pyrrolidineacetic acid 3-Pyrrolidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, (3R)- N-BOC-(R)-pyrrolidin-3-acetic acid 2-[(3S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid (R)-1-tert-Butoxycarbonylpyrrolidine-3-acetic acid 2-[(3R)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid (R)-3-carboxymethyl-pyrrolidin-1-carboxylic acid tert-butyl ester (R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid 204688-60-8 pharmacetical