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4-Fluoroacetophenone

4-Fluoroacetophenone Structure
CAS No.
403-42-9
Chemical Name:
4-Fluoroacetophenone
Synonyms
1-(4-Fluorophenyl)ethan-1-one;1-(4-FLUOROPHENYL)ETHANONE;4-Fluoracetophenon;P-FLUOROACETOPHENONE;4'-FLUOROACETOPHENONE;p-Fluoro;AKOS BBS-00003234;Fluoroacetophenone3;4-FLUOROCETOPHENONE;4-FLUOROACETOPHENONE
CBNumber:
CB6419110
Molecular Formula:
C8H7FO
Molecular Weight:
138.14
MOL File:
403-42-9.mol
MSDS File:
SDS
Modify Date:
2024/7/23 18:28:04

4-Fluoroacetophenone Properties

Melting point 4 °C
Boiling point 77-78 °C10 mm Hg(lit.)
Density 1.143 g/mL at 20 °C(lit.)
refractive index n20/D 1.511(lit.)
Flash point 160 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Liquid
Specific Gravity 1.138
color Clear colorless to slightly yellow
BRN 386013
InChIKey ZDPAWHACYDRYIW-UHFFFAOYSA-N
CAS DataBase Reference 403-42-9(CAS DataBase Reference)
NIST Chemistry Reference Ethanone, 1-(4-fluorophenyl)-(403-42-9)
EPA Substance Registry System 4'-Fluoroacetophenone (403-42-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-23
WGK Germany  3
TSCA  T
HazardClass  IRRITANT
HS Code  29147090
NFPA 704
2
2 0

4-Fluoroacetophenone price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F3207 4′-Fluoroacetophenone 99% 403-42-9 25G ₹2013.45 2022-06-14 Buy
Sigma-Aldrich(India) F3207 4′-Fluoroacetophenone 99% 403-42-9 100G ₹5564.05 2022-06-14 Buy
ALFA India ALF-A13950-36 4'-Fluoroacetophenone, 99% 403-42-9 500g ₹13758 2022-05-26 Buy
ALFA India ALF-A13950-22 4'-Fluoroacetophenone, 99% 403-42-9 100g ₹5550 2022-05-26 Buy
ALFA India ALF-A13950-14 4'-Fluoroacetophenone, 99% 403-42-9 25g ₹1798 2022-05-26 Buy
Product number Packaging Price Buy
F3207 25G ₹2013.45 Buy
F3207 100G ₹5564.05 Buy
ALF-A13950-36 500g ₹13758 Buy
ALF-A13950-22 100g ₹5550 Buy
ALF-A13950-14 25g ₹1798 Buy

4-Fluoroacetophenone Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

4-Fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

Synthesis_403-42-9
General procedure: Oximes (1.0 mmol), Amberlyst-15 (0.02 g), FPA53-NO2(0.02 g), and solvent (1.5 mL) were introduced into a 25-cm-high, 90-mL autoclave with a glass tube inside equipped with magnetic stirrer (Scheme 2). Then the autoclave was charged with oxygen to 0.1 MPa. The reaction mixture was stirred at desirable temperature for special time. Progress of the reaction was monitored by thin-layer chromatography (TLC) or gas chromatography (GC). After the reaction, the resin (Amberlyst-15 and FPA53-NO2) was separated from the reaction mixture by filtration and extracted with 3 mL CH3CN (2 1.5 ml). The solvent was removed under reduced pressure. The residue was further purified by column chromatography on silica gel (300 mesh) with hexane/ethyl acetate to give the corresponding carbonyl compounds.

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Acetophenone, 4'-fluoro- para-Fluoroacetophenone 4-FLUOROCETOPHENONE 4-FLUOROACETOPHENONE AKOS BBS-00003234 Fluoroacetophenone color less liq Fluoroacetophenone3 4'-Fluoroacetophenone 1-(4-Fluorophenyl)ethan-1-one 1-(4-Fluorophenyl)ethanone 4-Fluoroacetophenone,99% LABOTEST-BB LT01148215 p-Fluoro 4'-Fluoroacetophenone 99% Ethanone, 1-(4-fluorophenyl)- 1-(4-fluorophenyl)-ethanon 1-Acetyl-4-fluorobenzene 4-Acetylphenyl fluoride Methyl 4-fluorophenyl ketone 4-Acetylfluorobenzene 4-Fluorophenyl Methyl ketone 4-Fluorophenylethanal Methyl 4-fluorophenyl Of Fluoroacetophenone 1-(4-Fluorophenyl)ethan-1-one, 1-(4-Fluorophenyl)-1-oxoethane The fluorine acetophenone p-Fluorophenyl methyl ketone 4'-Fluoroacetophenone> 4'-Fluoroacetophenone, 99%, for synthesis Haloperidol Decanoate EP Impurity L Haloperidol Decanoate Impurity 12(Haloperidol Decanoate EP Impurity L) Lidocaine Pharmaceutical Drugs Bromperidol decanoate EP Impurity L TIANFU-CHEM 4-Fluoroacetophenone 4-Fluoroacetophenone pure, 98% P-FLUOROACETOPHENONE 4'-FLUOROACETOPHENONE 1-(4-Fluorophenyl)ethan-1-one 1-(4-FLUOROPHENYL)ETHANONE 4-Fluoracetophenon Haloperidol EP Impurity L Haloperidol Decanoate Impurity L 4-FLOURO ACETOPHENONE 4'-Fluoroacetophenone 403-42-9 C7 to C8 Carbonyl Compounds Building Blocks Organic Building Blocks Ketones Adehydes, Acetals & Ketones Fluorine Compounds C7 to C8 Carbonyl Compounds Ketones Acetophenone series Benzenes Aromatic Acetophenones & Derivatives (substituted) Organics ketone