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PANCREATIC POLYPEPTIDE, HUMAN

PANCREATIC POLYPEPTIDE, HUMAN Structure
CAS No.
75976-10-2
Chemical Name:
PANCREATIC POLYPEPTIDE, HUMAN
Synonyms
PP, HUMAN;PANCREATIC POLYPEPTIDE;Human pancreatic polypeptide;PANCREATIC POLYPEPTIDE, HUMAN;M.W. 4181.71 C185H287N53O54S2;Pancreatic polypeptide(human) (9CI);PANCREATIC POLYPEPTIDE, HUMAN USP/EP/BP;APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2;Pancreatic Polypeptide human, ≥95% (HPLC);Pancreatic Polypeptide huManPancreatic Polypeptide
CBNumber:
CB6764364
Molecular Formula:
C185H287N53O54S2
Molecular Weight:
4181.71098
MOL File:
75976-10-2.mol
Modify Date:
2024/7/2 8:55:14
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PANCREATIC POLYPEPTIDE, HUMAN Properties

storage temp. -15°C
solubility Water: 1 mg/ml
form Powder
color White to off-white
Water Solubility Soluble to 0.70 mg/ml in water

PANCREATIC POLYPEPTIDE, HUMAN Chemical Properties,Uses,Production

Description

Pancreatic polypeptide is an agonist of neuropeptide Y (NPY) receptors that reduces forskolin-induced cAMP accumulation in L-M(TK-) cells recombinantly expressing human and rat Y4 receptors (EC50s = 87.1 and 36.3 pM, respectively). It binds to Y1 and Y5 receptors with Ki values of 19 and 3.9 nM, respectively, for human and 50 and 2.4 nM, respectively, for rhesus monkey receptors. Pancreatic polypeptide also binds to rabbit Y1, Y2, Y4, and Y5 receptors (Kis = 0.39, 0.087, 0.79, and 0.24 nM, respectively). It induces contractile responses in isolated rat colon with EC50 values of 1.6 and 0.7 nM for ascending and descending colon segments, respectively. In vivo, pancreatic polypeptide (0.7-7 nmol, i.c.v.) increases food intake in rats.

PANCREATIC POLYPEPTIDE, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

PANCREATIC POLYPEPTIDE, HUMAN Suppliers

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Phygene 18059081430 China 1232 58 Inquiry
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Shenzhen Nexconn Pharmatechs Ltd 58
Cellmano Biotech Limited 58
Dideu Industries Group Limited 58
BOC Sciences 58
Zhejiang J&C Biological Technology Co.,Limited 58
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TargetMol Chemicals Inc. 58
Nanjing TGpeptide 58
Zhejiang Hangyu API Co., Ltd 58
Phygene 58

75976-10-2(PANCREATIC POLYPEPTIDE, HUMAN)Related Search:

PANCREATIC POLYPEPTIDE (AVIAN) PANCREATIC POLYPEPTIDE (BOVINE) PANCREATIC POLYPEPTIDE (31-36) (HUMAN) PANCREATIC POLYPEPTIDE (1-17)-(ALA31,AIB32)-NEUROPEPTIDE Y (18-36) (HUMAN) H-LEU-THR-ARG-PRO-ARG-TYR-OH
PANCREATIC POLYPEPTIDE (RANA TEMPORARIA) PANCREATIC POLYPEPTIDE, RAT (GLY1,SER3,22,GLN4,34,THR6,ALA19,TYR21,ALA23,31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN) TRIFLUOROACETATE SALT ([125I]-TYR)-PANCREATIC POLYPEPTIDE (HUMAN) PANCREATIC POLYPEPTIDE, HUMAN FRAGMENT 31-36
BIOTINYL-PANCREATIC POLYPEPTIDE (HUMAN) PANCREATIC POLYPEPTIDE, (HUMAN) [125I]- BIOTIN-PANCREATIC POLYPEPTIDE, HUMAN NEUROPEPTIDE Y (19-23)-(GLY1,SER3,GLN4,THR6,ALA31,AIB32,GLN34)-PANCREATIC POLYPEPTIDE (HUMAN) PANCREATIC POLYPEPTIDE, HUMAN,PANCREATIC POLYPEPTIDE, HUMAN SYNTHETIC >99%
ANTI-PANCREATIC POLYPEPTIDE, HUMAN
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M.W. 4181.71 C185H287N53O54S2 H-ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2 APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2 ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2 ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2 ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2 HUMAN PP, HUMAN PANCREATIC POLYPEPTIDE PANCREATIC POLYPEPTIDE, HUMAN H-Ala-Pro-Leu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 REF DUPL: H-Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 Pancreatic Polypeptide huManPancreatic Polypeptide Human pancreatic polypeptide Pancreatic polypeptide(human) (9CI) Pancreatic Polypeptide human, ≥95% (HPLC) PANCREATIC POLYPEPTIDE, HUMAN USP/EP/BP Pancreatic Polypeptide (human) (trifluoroaceate salt) 75976-10-2 C185H287N53O54S2 Natriuretic Peptides Peptides Amino Acids and Peptides Biochemicals and Reagents BioChemical Peptide Neuropeptide Y (NPY ) receptor Elisa Kit-Mouse Elisa Kit