O-Diphenylphosphinylhydroxylamine
- CAS No.
- 72804-96-7
- Chemical Name:
- O-Diphenylphosphinylhydroxylamine
- Synonyms
- (AMinooxy)diphenylphosphine oxide;O-(diphenylphosphoryl)hydroxylaMine;aMino diphenylphosphinate;phosphinyL;diphenylphosphinate;O-DiphenyL;Azanyl P,P-diphenylphosphinate;(AMinooxy)diphenylphosphineoxid;TwoPhenylphosphonichydroxylaMine;O-DIPHENYLPHOSPHINYLHYDROXYLAMIN
- CBNumber:
- CB7219861
- Molecular Formula:
- C12H12NO2P
- Molecular Weight:
- 233.2
- MOL File:
- 72804-96-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/29 14:44:33
| Melting point | >140℃ (decomposition) |
|---|---|
| Boiling point | 368.0±25.0 °C(Predicted) |
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly, Sonicated) |
| pka | -1.65±0.70(Predicted) |
| form | solid |
| color | white |
| InChI | InChI=1S/C12H12NO2P/c13-15-16(14,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,13H2 |
| InChIKey | SJECIYLGISUNRO-UHFFFAOYSA-N |
| SMILES | P(C1=CC=CC=C1)(C1=CC=CC=C1)(ON)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H312 |
| Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P |
| WGK Germany | 3 |
O-Diphenylphosphinylhydroxylamine Chemical Properties,Uses,Production
Chemical Properties
Light yellow or white powder solid
Uses
O-Diphenylphosphinylhydroxylamine is a versatile reactant used in the synthetic preparation of various products such as trans-acylaziridines and aldohydrazones.
Description
O-Diphenylphosphinylhydroxylamine (DPPH) is a versatile electrophilic amination reagent that has been used widely for the amination of stable carbanions, Grignard reagents, and π-electron-rich nitrogen heterocycles. Researchers have used DPPH for the aziridination of enones. Compared to other hydroxylamine derivatives typically stored as hydrochloride salts, this activated phosphinyl reagent exhibits good stability and can be stored indefinitely at 0 ℃. This compound in a single step from hydroxylamine hydrochloride and diphenylphosphinic chloride[1].
General Description
O-(Diphenylphosphinyl)hydroxylamine is a general reagent for electrophilic C-amination, which aminates a variety of stable carbanions and Grignard reagents.
References
[1] J. P. Anselm, J. L. Ferrari. “A New Journal for Organic Synthesis: Organic Preparations and Procedures International.” Journal of Chemical Education 48 5 (1971): 349.
O-Diphenylphosphinylhydroxylamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | China | 1206 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2141 | 58 | Inquiry |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | China | 2931 | 58 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
| Accela ChemBio Inc. | +1-858699-3322 +86-18019713315 | United States | 19313 | 58 | Inquiry |