1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Structure
CAS No.
100991-92-2
Chemical Name:
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
Synonyms
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE;2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride;1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor;3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R)-;(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine hydrochloride
CBNumber:
CB7230309
Molecular Formula:
C5H12ClNO3
Molecular Weight:
169.61
MOL File:
Mol file
Modify Date:
2023/5/18 11:31:12

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Properties

Melting point 110-112 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1))
storage temp. 2-8°C
solubility DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
form A crystalline solid

SAFETY

Risk and Safety Statements

WGK Germany  3

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) D1542 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor 100991-92-2 10MG ₹62406.13 2022-06-14 Buy
Sigma-Aldrich(India) D1542 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor 100991-92-2 25MG ₹137477.5 2022-06-14 Buy
Product number Packaging Price Buy
D1542 10MG ₹62406.13 Buy
D1542 25MG ₹137477.5 Buy

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Chemical Properties,Uses,Production

Description

1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.

Uses

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.

General Description

1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Suppliers

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100991-92-2(1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE)Related Search:

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE 2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride (2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine hydrochloride 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R)- 100991-92-2