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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Structure
CAS No.
123367-26-0
Chemical Name:
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Synonyms
Imatinib impurity J;Irutinib Impurity A;(E)-3-(dimethylamino);Imatinib EP impuritiesA;Imatinib Mesilate EP Impurity A;Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib EP Impurity A (Nilotinib Impurity 16);(E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one;(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one;(2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one
CBNumber:
CB72516261
Molecular Formula:
C10H12N2O
Molecular Weight:
176.22
MOL File:
123367-26-0.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02
Request For Quotation

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Properties

Melting point 113℃
Boiling point 281℃
Density 1.070
Flash point 124℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 4.74±0.70(Predicted)
color Dark Brown to Very Dark Brown

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties,Uses,Production

Description

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is a pharmaceutical intermediate used as an intermediate of nilotinib, a targeted anticancer drug for the treatment of chronic myeloid leukaemia (CML).

Uses

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents.

Solubility in organics

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is soluble in chloroform and dichloromethane.

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Suppliers

Global( 107)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Capot Chemical Co.,Ltd. +86-（0）57185586718 +86-13336195806 China 29730 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21628 55 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29808 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23541 58 Inquiry
Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9414 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418684 +8618949823763 China 25356 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Capot Chemical Co.,Ltd. 60
Henan Tianfu Chemical Co.,Ltd. 55
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
ANHUI WITOP BIOTECH CO., LTD 58
Baoji Guokang Healthchem co.,ltd 58
Hefei TNJ Chemical Industry Co.,Ltd. 58

123367-26-0((2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one)Related Search:

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 2-Propen-1-one, 1-[(3R)-3-[4-amino-7-oxido-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- Imatinib Impurity 38 Ibrutinib Impurity 28 (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone
Imatinib Impurity 4 Ibrutinib Impurity 5 Ibrutinib Dimer Impurity Imatinib Impurity 7 (S)-Ibrutinib
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one N-(2-Methyl-4-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine N-DESMETHYL IMATINIB 4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide Ilutinib Methylxanthate Impurity C
Ibrutinib Impurity D N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
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(2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one (2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib) (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one Nilotinib IMpurity ((2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one) Imatinib EP Impurity A (Nilotinib Impurity 16) Nilotinib Impurity 16 (Imatinib EP Impurity A) Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one (E)-3-(dimethylamino) Irutinib Impurity A Imatinib impurity J 2-Propen-1-one, 3-(dimethylamino)-1-(3-pyridinyl)-, (2E)- (E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one Imatinib EP impuritiesA (2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one Imatinib Mesilate EP Impurity A 123367-26-0