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PS 48

PS 48 Structure
CAS No.
1180676-32-7
Chemical Name:
PS 48
Synonyms
PS 48;CS-1466;PS 48;PS-48;PS-48;PS 48;PS48;5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid;(Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid;(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid;2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)-
CBNumber:
CB72518801
Molecular Formula:
C17H15ClO2
Molecular Weight:
286.75
MOL File:
1180676-32-7.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:22
Request For Quotation

PS 48 Properties

Melting point 114-115℃
Boiling point 444.1±24.0 °C(Predicted)
Density 1.225±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
pka 4.55±0.10(Predicted)
form powder
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

PS 48 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P0022 PS48 ≥98% (HPLC) 1180676-32-7 5MG ₹13726.1 2022-06-14 Buy
Sigma-Aldrich(India) P0022 PS48 ≥98% (HPLC) 1180676-32-7 25MG ₹56333.3 2022-06-14 Buy
Product number Packaging Price Buy
P0022 5MG ₹13726.1 Buy
P0022 25MG ₹56333.3 Buy

PS 48 Chemical Properties,Uses,Production

Uses

PS 48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator.

Biochem/physiol Actions

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

PS 48 Preparation Products And Raw materials

Raw materials

3-(4-CHLOROPHENYL)PROPIOPHENONE 4-Chlorochalcone

Preparation Products

PS 48 Suppliers

Global( 90)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Aloespharm Co., Ltd. 021-20960837 China 1303 55 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
TargetMol Chemicals Inc. 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Aloespharm Co., Ltd. 55
(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid PS 48 (Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid PS 48;PS-48 PS-48;PS 48;PS48 CS-1466 2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)- 1180676-32-7