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Cibenzoline succinate

Cibenzoline succinate Structure
CAS No.
100678-32-8
Chemical Name:
Cibenzoline succinate
Synonyms
ritmalan;ole(1:1);cipralan;Cinobezile;ro22-7796/001;Cibenzoline succinate;cibenzolinesuccinate(1:1);(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1);4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate;4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate
CBNumber:
CB7255168
Molecular Formula:
C22H24N2O4
Molecular Weight:
380.44
MOL File:
100678-32-8.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:56
Request For Quotation

Cibenzoline succinate Properties

Melting point 165°
storage temp. 2-8°C
solubility H2O: ≥5mg/mL
form solid
color white to off-white
Stability Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  EJ9960100

Cibenzoline succinate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C1618 Cibenzoline succinate ≥98% (HPLC), solid 100678-32-8 10MG ₹15761.2 2022-06-14 Buy
Sigma-Aldrich(India) C1618 Cibenzoline succinate ≥98% (HPLC), solid 100678-32-8 50MG ₹70827.98 2022-06-14 Buy
Product number Packaging Price Buy
C1618 10MG ₹15761.2 Buy
C1618 50MG ₹70827.98 Buy

Cibenzoline succinate Chemical Properties,Uses,Production

Uses

Cibenzoline Succinate acts as a highly active class I antiarrhythmic agent.

General Description

Cibenzoline also called (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate, is generally used in stereo combination of R(+) and S(?) forms. It also exhibits anticholinergic activity.. Cibenzoline is known to improve left ventricular diastolic dysfunction by reducing left ventricular pressure gradient.

Biochem/physiol Actions

Cibenzoline is a class IA antiarrhythmic drug. Cibenzoline (μM concentrations) blocks ATP-sensitive K channels in heart and pancreatic cells. Cibenzoline interacts with the channel pore-forming subunit of the K(ATP) channel (Kir6.2) from the cytoplasmic side. Cibenzoline also inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells.

Cibenzoline succinate Preparation Products And Raw materials

Raw materials

Preparation Products

Cibenzoline succinate Suppliers

Global( 32)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 China 40857 58 Inquiry
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 China 40041 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry
Mitsubishi Chemical Europe GmbH 49-211-5205410 Germany 1252 58 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
CONIER CHEM AND PHARMA LIMITED 58
Career Henan Chemica Co 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Shanghai Haohong Scientific Co., Ltd. 58
Energy Chemical 58
Sigma-Aldrich 80
Mitsubishi Chemical Europe GmbH 58
United States Biological 80

100678-32-8(Cibenzoline succinate)Related Search:

Cefazolin Dioctyl sulfosuccinate sodium salt 6alpha-Methylprednisolone sodium succinate Cefazolin sodium salt Tolazoline hydrochloride
Dichlorodiphenylsilane Metroprolol succinate Succinic acid iron succinate 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
Disodium succinate Chlorodiphenylphosphine Imidazole Oxymetazoline hydrochloride BUTYRAMIDINE
Cibenzoline Cibenzoline succinate 4-methylpentanimidamide
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(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1) ole(1:1) ritmalan ro22-7796/001 succinic acid, compound with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2) 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate, Cibenol, Cipralan, Exacor Cinobezile Cibenzoline succinate 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazol(+-)-1h-imidazolbutanedioate( 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidaz butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazole(1:1) cibenzolinesuccinate(1:1) cipralan 100678-32-8 C18H18N2C4H6O4 Cell Biology Cell Signaling and Neuroscience BioChemical Voltage-gated Ion Channels Potassium Channel Modulators Ion Channels Monovalent Ion Channels Heterocyclic Compounds