(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile

CAS No.: 1640971-60-3

Chemical Name:: (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile

Synonyms: tofacitinib iMpurity;Tofacitinib Impurity 21;PF-05579970;Tofatib reference;ofacitinib iMpurity;Tofaimpurity iMpurity;Tofatinib Impurity 21;Tofacitinib Impurity 9;Tofacitinib ImpurityBA;Tofacitinib Impurity 18

CBNumber:: CB72663305

Molecular Formula:: C14H20N6O

Molecular Weight:: 288.35

MOL File:: 1640971-60-3.mol

Modify Date:: 2025/2/12 15:25:52

Request For Quotation

(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Properties

Melting point	238 - 240°C
Boiling point	551.0±50.0 °C(Predicted)
Density	1.249±0.06 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	6.06±0.60(Predicted)
form	Solid
color	White to Off-White

(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Chemical Properties,Uses,Production

Uses

Tofacitinib Citrate Impurity is derived from (3R,?4R)?-N,?4-?Dimethyl-?1-?benzyl?-3-?piperidinamine (D464895), which is a reagent used in the preparation of Janus tyrosine kinase inhibitors for the treatment of autoimmune diseases.

(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Preparation Products And Raw materials

Raw materials

Preparation Products

(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Suppliers

Global( 93)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6514	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6739	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
Moxin Chemicals	+8617320513646	China	10886	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29808	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23541	58	Inquiry
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15393	58	Inquiry
CR Corporation Limited	+8613062833949	China	8647	58	Inquiry
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11922	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43340	58	Inquiry

Supplier	Advantage
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEARSYNTH LABS LTD.	58
Moxin Chemicals	58
career henan chemical co	58
ANHUI WITOP BIOTECH CO., LTD	58
AFINE CHEMICALS LIMITED	58
CR Corporation Limited	58
China National Standard Pharmaceutical Corporation Limited	58
LEAPCHEM CO., LTD.	58

1640971-60-3((3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile)Related Search:

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Tenofovirdisoproxil Impurity LUMACAFTOR IMPURITY Dapagliflozin iMpurity N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine (3S,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine

N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile Tofacitinib related coMpound 2

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ofacitinib iMpurity Tofacitinib Citrate Impurity Tofacitinib Impurity 11 Tofacitinib Impurity 14 Tofacitinib Impurity 15 Tofacitinib Impurity 18 Tofacitinib Impurity 9 3-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl) (methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate-one Tofacitinib Impurity TBA Tofacitinib Impurity 5 DiHCl N2,N4-bis((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N2,N4-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine PF-05579970 3-((3R,4R)-4-methyl-3-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Tofaimpurity iMpurity Tofacitinib Related Compound 11 butyl (E)-3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate Tofacitinib Impurity TAB 1-Piperidinepropanenitrile, 3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-, (3R,4R)- Tofatib reference Tofacitinib Impurities1006 Tofacitinib Impurities1007 Tofacitinib Impurities1008 Tofacitinib Impurities1009 3-[3-((6-Amino-pyrimidin-4-yl)-methyl-amino)-4-methyl-piperidin-1-yl]-3-oxo-propionitrile tofacitinib iMpurity Tofacitinib Impurity 21 Tofatinib Impurity 21 (3R,4R)-3-[(6-Amino-4-pyrimidinyl)methylamino]-4-methyl-Beta-oxo-1-piperidinepropanenitrile (3RS,4SR)-1-benzyl-N,4-dimethylpiperidin-3-amine Tofacitinib ImpurityBA 3-((3R,4R)-3-((6-Aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile (Tofacitinib Impurity） 1640971-60-3 ZJ ZY