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1,2-Bis(piperazin-1-yl)benzene

1,2-Bis(piperazin-1-yl)benzene Structure
CAS No.
1446750-99-7
Chemical Name:
1,2-Bis(piperazin-1-yl)benzene
Synonyms
Vortioxetine Impurity;Vortioxetine Impurity 20;VortioxetineImpurity20DiHCl;1,2-di(piperazin-1-yl)benzene;1,2-Bis(piperazin-1-yl)benzene;1,1'-(1,2-Phenylene)dipiperazine;Piperazine, 1,1'-(1,2-phenylene)bis-;Piperazine, 1,1'-(1,2-phenylenE)bis-;1,2-di(piperazin-1-yl)benzene dihydrochloride;1,2-Di(piperazin-1-yl)benzene (Vortioxetine Impurity)
CBNumber:
CB72713213
Molecular Formula:
C14H22N4
Molecular Weight:
246.35
MOL File:
1446750-99-7.mol

1,2-Bis(piperazin-1-yl)benzene Properties

Boiling point 432.6±40.0 °C(Predicted)
Density 1.089±0.06 g/cm3(Predicted)
pka 9.22±0.10(Predicted)

1,2-Bis(piperazin-1-yl)benzene Chemical Properties,Uses,Production

Uses

1,2-Di(piperazin-1-yl)benzene is an impurity of the antidepressant vortioxetine .

1,2-Bis(piperazin-1-yl)benzene Preparation Products And Raw materials

Raw materials

Preparation Products

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Piperazine, 1,1'-(1,2-phenylene)bis- Vortioxetine Impurity 20 1,1'-(1,2-Phenylene)dipiperazine Vortioxetine Impurity R: 1- (2-piperazine-1-phenyl) piperazine 1,2-di(piperazin-1-yl)benzene VortioxetineImpurity20DiHCl 1,2-Di(piperazin-1-yl)benzene (Vortioxetine Impurity) 1,2-di(piperazin-1-yl)benzene dihydrochloride Piperazine, 1,1'-(1,2-phenylenE)bis- Vortioxetine Impurity N1-(2-chloroethyl)-N2-(2-((2-chloroethyl)amino)ethyl)-N2-(2-((2,4-dimethylphenyl)thio)phenyl)ethane-1,2-diamine 1,2-Bis(piperazin-1-yl)benzene 1446750-99-7