TRYPSINOGEN
- CAS No.
- 9002-08-8
- Chemical Name:
- TRYPSINOGEN
- Synonyms
- TRYPSINOGEN;Ttrypsinogen;TRYPSINOGEN FROM BEEF PANCREAS;trypsinogen from bovine pancreas;Trypsinogen >2500 U/mg from bovine;Trypsinogen >2500U/mg from bovine pancreas;Trypsinogen, PMSF treated from bovine pancreas
- CBNumber:
- CB7282580
- Molecular Formula:
- C39H55N9O17
- Molecular Weight:
- 921.9
- MOL File:
- 9002-08-8.mol
- Modify Date:
- 2023/4/23 13:52:06
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H315-H319-H334 |
Precautionary statements | P302+P352-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 36/37/38-42 |
Safety Statements | 22-24-26-36/37 |
WGK Germany | 3 |
F | 10-21 |
TRYPSINOGEN price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | T1143 | Trypsinogen from bovine pancreas essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin) | 9002-08-8 | 250MG | ₹23619.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T9011 | Trypsinogen, PMSF treated from bovine pancreas For use as a marker in SDS-PAGE | 9002-08-8 | 1VIAL | ₹57767 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T1143 | Trypsinogen from bovine pancreas essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin) | 9002-08-8 | 1G | ₹77628.6 | 2022-06-14 | Buy |
TRYPSINOGEN Chemical Properties,Uses,Production
Uses
Trypsinogen from bovine pancreas is suitable for use in:
- the secondary structure analysis of proteins in H2O solution using single-pass attenuated total reflection Fourier transform infrared (ATR-FT-IR) microscopy
- tuning and calibration of electrospray ionization quadrupole time-of-flight (ESI-Q-TOF) mass spectrometer
- the secondary structure analysis of proteins by infrared (IR) spectroscopy
- SDS-PAGE as a molecular weight standard (24kDa)
General Description
Trypsinogen is a proenzyme (zymogen) that is activated to form trypsin. It is synthesized in the pancreas and activated by enterokinase once it reaches the lumen of the small intestine. Bovine trypsinogen is a single polypeptide chain of 229 amino acids that is cross linked by six disulfide bridges. Enterokinase cleaves a hexapeptide to from the NH2 terminus of trypsinogen at the Lys6 - Ile7 peptide bond and activates it. Trypsin, thus formed, autocatalytically activates more trypsinogen to trypsin. This native form of trypsin is called β-trypsin, which undergoes autolysis at Lys131 - Ser132 resulting in α-trypsin that is held together by disulfide bridges. Trypsin is a serine protease with His46 and Ser183 at the active site. The pH optimum of trypsin is 7 - 9.
Biochem/physiol Actions
Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.
TRYPSINOGEN Preparation Products And Raw materials
Raw materials
Preparation Products
TRYPSINOGEN Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
MP Biomedicals, Inc. | 949 833 2500 | United States | 6566 | 81 | Inquiry |
Pfaltz & Bauer, Inc. | (800) 225-5172 | United States | 6830 | 72 | Inquiry |
Worthington Biochemical Corporation | 800 445 9603 | United States | 109 | 77 | Inquiry |
AppliChem GmbH | +49 6151 93 57 0 | Germany | 1607 | 74 | Inquiry |
Service Chemical Inc. | 888-895-6920 | Germany | 6373 | 71 | Inquiry |
AppliChem GmbH | +1 203-271-2224 | Germany | 970 | 65 | Inquiry |
MOLEKULA Ltd. | +44 (0) 1747 831066 | United Kingdom | 6152 | 66 | Inquiry |
SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6913 | 91 | Inquiry |
Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |
Raw material medicin reagent co.,Ltd | China | 4531 | 58 | Inquiry |
Supplier | Advantage |
---|---|
MP Biomedicals, Inc. | 81 |
Pfaltz & Bauer, Inc. | 72 |
Worthington Biochemical Corporation | 77 |
AppliChem GmbH | 74 |
Service Chemical Inc. | 71 |
AppliChem GmbH | 65 |
MOLEKULA Ltd. | 66 |
SIGMA-RBI | 91 |
Riedel-de Haen AG | 87 |
Raw material medicin reagent co.,Ltd | 58 |