TRYPSINOGEN

TRYPSINOGEN Structure
CAS No.
9002-08-8
Chemical Name:
TRYPSINOGEN
Synonyms
TRYPSINOGEN;Ttrypsinogen;TRYPSINOGEN FROM BEEF PANCREAS;trypsinogen from bovine pancreas;Trypsinogen >2500 U/mg from bovine;Trypsinogen >2500U/mg from bovine pancreas;Trypsinogen, PMSF treated from bovine pancreas
CBNumber:
CB7282580
Molecular Formula:
C39H55N9O17
Molecular Weight:
921.9
MOL File:
9002-08-8.mol
Modify Date:
2023/4/23 13:52:06

TRYPSINOGEN Properties

storage temp. 2-8°C
form essentially salt-free, lyophilized powder

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H315-H319-H334
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-42
Safety Statements  22-24-26-36/37
WGK Germany  3
10-21

TRYPSINOGEN price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T1143 Trypsinogen from bovine pancreas essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin) 9002-08-8 250MG ₹23619.2 2022-06-14 Buy
Sigma-Aldrich(India) T9011 Trypsinogen, PMSF treated from bovine pancreas For use as a marker in SDS-PAGE 9002-08-8 1VIAL ₹57767 2022-06-14 Buy
Sigma-Aldrich(India) T1143 Trypsinogen from bovine pancreas essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin) 9002-08-8 1G ₹77628.6 2022-06-14 Buy
Product number Packaging Price Buy
T1143 250MG ₹23619.2 Buy
T9011 1VIAL ₹57767 Buy
T1143 1G ₹77628.6 Buy

TRYPSINOGEN Chemical Properties,Uses,Production

Uses

Trypsinogen from bovine pancreas is suitable for use in:

  • the secondary structure analysis of proteins in H2O solution using single-pass attenuated total reflection Fourier transform infrared (ATR-FT-IR) microscopy
  • tuning and calibration of electrospray ionization quadrupole time-of-flight (ESI-Q-TOF) mass spectrometer
  • the secondary structure analysis of proteins by infrared (IR) spectroscopy
  • SDS-PAGE as a molecular weight standard (24kDa)

General Description

Trypsinogen is a proenzyme (zymogen) that is activated to form trypsin. It is synthesized in the pancreas and activated by enterokinase once it reaches the lumen of the small intestine. Bovine trypsinogen is a single polypeptide chain of 229 amino acids that is cross linked by six disulfide bridges. Enterokinase cleaves a hexapeptide to from the NH2 terminus of trypsinogen at the Lys6 - Ile7 peptide bond and activates it. Trypsin, thus formed, autocatalytically activates more trypsinogen to trypsin. This native form of trypsin is called β-trypsin, which undergoes autolysis at Lys131 - Ser132 resulting in α-trypsin that is held together by disulfide bridges. Trypsin is a serine protease with His46 and Ser183 at the active site. The pH optimum of trypsin is 7 - 9.

Biochem/physiol Actions

Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.

TRYPSINOGEN Preparation Products And Raw materials

Raw materials

Preparation Products

TRYPSINOGEN Suppliers

Global( 25)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
MP Biomedicals, Inc. 949 833 2500 United States 6566 81 Inquiry
Pfaltz & Bauer, Inc. (800) 225-5172 United States 6830 72 Inquiry
Worthington Biochemical Corporation 800 445 9603 United States 109 77 Inquiry
AppliChem GmbH +49 6151 93 57 0 Germany 1607 74 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
AppliChem GmbH +1 203-271-2224 Germany 970 65 Inquiry
MOLEKULA Ltd. +44 (0) 1747 831066 United Kingdom 6152 66 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Raw material medicin reagent co.,Ltd China 4531 58 Inquiry
TRYPSINOGEN trypsinogen from bovine pancreas TRYPSINOGEN FROM BEEF PANCREAS Trypsinogen, PMSF treated from bovine pancreas Trypsinogen >2500U/mg from bovine pancreas Trypsinogen >2500 U/mg from bovine Ttrypsinogen 9002-08-8 Protein Analysis Proteases & Protein Sequencing Proteases Peptide and protein standards for mass spectrometry analysis Mass Spectrometry Enzymes, Inhibitors, and Substrates Proteomics and Protein Expression Application Index Biochemicals and Reagents BioChemical Auxiliary Proteins Other Proteins and Derivatives Peptide and protein standards for mass spectrometry analysisApplication Index Mass Spectrometry Proteases Proteases&Protein Sequencing Proteomics