AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE

- CAS No.
- 131602-53-4
- Chemical Name:
- AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE
- Synonyms
- Aβ25-35;BETA-AMYLOID;GSNKGAIIGLM;-Amyloid(25-35);β-Amyloid (25-35);BETA-AMYLOID (25-35);β-Amyloid (25-35) TFA;25-35) TRIFLUOROACETATE;β-Amyloid peptide(25-35);AMyloid b-Protein (25-35)
- CBNumber:
- CB7297245
- Molecular Formula:
- C45H81N13O14S
- Molecular Weight:
- 1060.27
- MOL File:
- 131602-53-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
Boiling point | 1517.3±65.0 °C(Predicted) |
---|---|
Density | 1.248±0.06 g/cm3(Predicted) |
RTECS | BU7435200 |
storage temp. | -20°C |
solubility | insoluble in EtOH; insoluble in H2O; ≥106 mg/mL in DMSO |
form | Lyophilized. |
pka | 3.24±0.10(Predicted) |
color | Lyophilized White |
Water Solubility | Soluble in water. |
Sequence | H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH |
InChIKey | WIHBNMPFWRHGDF-SLVFWPMISA-N |
AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A4559 | Amyloid β-Protein Fragment 25-35 ≥97% (HPLC) | 131602-53-4 | 250μG | ₹6971.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A4559 | Amyloid β-Protein Fragment 25-35 ≥97% (HPLC) | 131602-53-4 | 1MG | ₹19214.38 | 2022-06-14 | Buy |
AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Chemical Properties,Uses,Production
Uses
Amyloid β-Protein Fragment 25-35 has been used:
- to induce neurotoxicity in cortical cultures
- to induce Alzheimer′s disease in rat model
- to induce apoptosis in mesenchymal stem cells (MSCs)
General Description
Amyloid β-Protein Fragment 25-35 (Aβ25-35) is derived from the amyloid-β protein.amyloid-β protein, which is mapped to human chromosome 21q21. Aβ25-35 lacks the N-terminal domain and the metal binding site and is majorly generated by proteolytic cleavage of Aβ(1?40) peptides. It has a β-sheet and β-turn structure.
Biochem/physiol Actions
Amyloid β-Protein Fragment 25-35 (Aβ25-35) is involved in the pathogenesis of Alzheimer′s disease. Inhibitors of this transition may serve as a potential agent in managing Alzheimer′s disease. It is present in the subiculum and entorhinal cortex neurons of Alzheimer′s brain samples and inclusion-body myositis (IBM) muscle. It binds to receptors present in microglia and is capable of lipid membrane insertion. The functional domain sequence of Aβ comprising of sequence GSNKGAIIGLM elicits neurotrophic and neurotoxic effects. Aβ25-35 exhibits rapid aggregation and displays age dependant neurotoxicity.
AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12809 | 58 | Inquiry |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | China | 10983 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10406 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | China | 2555 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10244 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22854 | 58 | Inquiry |
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