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GNE-495

GNE-495 Structure
CAS No.
1449277-10-4
Chemical Name:
GNE-495
Synonyms
GNE-495;GNE-495;GNE 495;GNE495;MAPK Kinase Kinase Kinase,MAP4K,inhibit,GNE-495,GNE 495,GNE495,Inhibitor;8-Amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide;8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide;1,7-Naphthyridine-5-carboxamide, 8-amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)-
CBNumber:
CB73144856
Molecular Formula:
C22H20FN5O2
Molecular Weight:
405.42
MOL File:
1449277-10-4.mol
Modify Date:
2024/7/2 8:55:16
Request For Quotation

GNE-495 Properties

Boiling point 734.5±60.0 °C(Predicted)
Density 1.45±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:3.59(Max Conc. mg/mL);8.85(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:7):0.125(Max Conc. mg/mL);0.31(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);12.33(Max Conc. mM)
Water:1.0(Max Conc. mg/mL);2.47(Max Conc. mM)
form A crystalline solid
pka 11.60±0.20(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H318
Precautionary statements  P280-P301+P310-P330-P305+P351+P338-P310
HS Code  2933998090
NFPA 704
0
2 0

GNE-495 Chemical Properties,Uses,Production

GNE-495 Preparation Products And Raw materials

Raw materials

2-Bromo-5-fluoropyridine (3-amino-1-azetidinyl)cyclopropylmethanone 3-Fluorophenylboronic acid

Preparation Products

GNE-495 Suppliers

Global( 49)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10991 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Suzhou ARTK Medchem Co., Ltd. +8618168183658 China 39010 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 5225 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
InvivoChem 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Zibo Hangyu Biotechnology Development Co., Ltd 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58
Suzhou ARTK Medchem Co., Ltd. 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58
Amadis Chemical Company Limited 58

GNE-495 Spectrum

GNE-495(1449277-10-4)1HNMR
GNE-495 8-Amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide GNE-495;GNE 495;GNE495 1,7-Naphthyridine-5-carboxamide, 8-amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)- MAPK Kinase Kinase Kinase,MAP4K,inhibit,GNE-495,GNE 495,GNE495,Inhibitor 1449277-10-4