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(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Structure
CAS No.
1223404-90-7
Chemical Name:
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine
Synonyms
Larotrectinib DFP-PNPP Impurity;Larotrectinib Impurity 3（Larotrectinib DFP-PNPP Impurity）;[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitropyrazolo[1,5-a]pyrimidine;(R)-5-(2-(2,5-Difluorophenyl)-1-pyrrolidinyl)-3-nitropyrazolo[1,5-a]pyrimidine;(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine;(2R)-2-(2,5-difluorophenyl)-1-{3-nitropyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine;(R)-3-nitro-5-[2-(2,5-difluorophenyl)-1-pyrrolidine]pyrazoleand[1,5-a]pyrimidine;5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitr opyrazolo[1,5-a]pyrimidine;Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-nitro-
CBNumber:
CB73167712
Molecular Formula:
C16H13F2N5O2
Molecular Weight:
345.3
MOL File:
1223404-90-7.mol
Modify Date:
2022/12/21 16:56:50
Request For Quotation

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Properties

Density 1.58±0.1 g/cm3(Predicted)
pka -0.73±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Chemical Properties,Uses,Production

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Preparation Products And Raw materials

Raw materials

4H-Pyrazolo[1,5-a]pyrimidin-5-one (2R)-2-(2,5-difluorophenyl)-1-{pyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole 3-nitropyrazolo[1,5-a]pyrimidin-5(4H)-one 2,5-Difluorobenzaldehyde
(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE (2R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE 5-Hydroxypyrazolo[1,5-a]pyrimidine 1-Bromo-2,5-difluorobenzene
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Preparation Products

Larotrectinib Sulfate

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Suppliers

Global( 54)Suppliers
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ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7621 58 Inquiry
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Neostar United (Changzhou) Industrial Co., Ltd. +86-0519-85551759 +8613506123987 China 9505 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +8617531190177 China 5873 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
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Jiangxi Huihe Chemical Co., Ltd. +86-19189228086 +8618858568638 China 886 58 Inquiry
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Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
Jinan Carbotang Biotech Co.,Ltd. 58
career henan chemical co 58
Neostar United (Changzhou) Industrial Co., Ltd. 58
Hebei Yanxi Chemical Co., Ltd. 58
Career Henan Chemica Co 58
Shanghai Rochi Pharmaceutical Co.,Ltd. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Jiangxi Huihe Chemical Co., Ltd. 58
Shandong Risen-Sun Pharmaceutical Co., Ltd 58
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine (2R)-2-(2,5-difluorophenyl)-1-{3-nitropyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine 5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitr opyrazolo[1,5-a]pyrimidine Larotrectinib Impurity 3（Larotrectinib DFP-PNPP Impurity） (R)-5-(2-(2,5-Difluorophenyl)-1-pyrrolidinyl)-3-nitropyrazolo[1,5-a]pyrimidine Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-nitro- Larotrectinib DFP-PNPP Impurity [(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitropyrazolo[1,5-a]pyrimidine (R)-3-nitro-5-[2-(2,5-difluorophenyl)-1-pyrrolidine]pyrazoleand[1,5-a]pyrimidine 1223404-90-7