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CIS-ENTACAPONE

CIS-ENTACAPONE Structure
CAS No.
145195-63-7
Chemical Name:
CIS-ENTACAPONE
Synonyms
CIS-ENTACAPONE;(Z)-Entacapone;Entacapen impurity A;Entacapone-d10 (cis);Entacapone impurity A;Entacapone impurity A -I;Entacapone EP IMpurity A;Entacapone impurity A CRS;Entacapone Related CoMpound A;Z Entacapone/ EP impurity A/RC A
CBNumber:
CB7334326
Molecular Formula:
C14H15N3O5
Molecular Weight:
305.29
MOL File:
145195-63-7.mol
Modify Date:
2023/7/12 16:52:05

CIS-ENTACAPONE Properties

Melting point 142-144°C
Boiling point 526.6±50.0 °C(Predicted)
Density 1.392±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Dichloromethane (Slightly), Methanol (Slightly)
pka 5.15±0.50(Predicted)
color Yellow to Orange

SAFETY

Risk and Safety Statements

HS Code  2926900005

CIS-ENTACAPONE Chemical Properties,Uses,Production

Description

cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone . It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.

Chemical Properties

Orange Solid

Uses

cis-Entacapone (Entacapone EP Impurity A) is the (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian.

CIS-ENTACAPONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 85)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Chemicea Pharmaceuticals Pvt Ltd +91-918482849343 +91-8482849343 Mumbai, India 461 58 Inquiry
GLP Pharma Standards +91 9866074638 Hyderabad, India 1644 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Chemicea Pharmaceuticals Pvt Ltd +91-9881765045/+91-8796656135 Pune, India 825 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide (Z)-Entacapone CIS-ENTACAPONE Entacapone Related Compound A (25 mg) ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide) Entacapone EP IMpurity A Entacapone Related CoMpound A Entacapone impurity A Entacapone impurity A -I (Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide Entacapone Impurity 17(Entacapone EP Impurity A) Entacapone Impurity 1(Entacapone EP Impurity A) Entacapone EP Impurity A (cis-Entacapone) Entacapone impurity A CRS (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nit 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2Z)- Entacapen impurity A Z Entacapone/ EP impurity A/RC A (Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide Entacapone-d10 (cis) Entacapone Related Compound A ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide) (1235944) Entacapone USP Related Compound A Entacapone Z-isomer / Entacapone Related Compound-A / Entacapone EP Impurity-A Entacapone EP Impurity A (Entacapone USP Related Compound A, cis-Entacapone) 145195-63-7 C14H15N3O5 Intermediates & Fine Chemicals Pharmaceuticals