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Methotrexate α-tert-Butyl Ester

Methotrexate α-tert-Butyl Ester Structure
CAS No.
79640-70-3
Chemical Name:
Methotrexate α-tert-Butyl Ester
Synonyms
Methotrexate Impurity 8;Methotrexate α-tert-Butyl Ester;Methotrexate a-tert-Butyl Ester;Methotrexate α-tert-Butyl Ester;(S)-5-(tert-butoxy)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid;L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-(1,1-dimethylethyl) ester
CBNumber:
CB76091801
Molecular Formula:
C24H30N8O5
Molecular Weight:
510.55
MOL File:
79640-70-3.mol
Modify Date:
2023/5/12 11:12:40
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Methotrexate α-tert-Butyl Ester Properties

Melting point >211°C (dec.)
Density 1.377±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 4.43±0.10(Predicted)
color Pale Yellow to Orange

Methotrexate α-tert-Butyl Ester Chemical Properties,Uses,Production

Uses

Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.

Methotrexate α-tert-Butyl Ester Preparation Products And Raw materials

Raw materials

H-Glu(OMe)-OtBu 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID L-Glutamic acid α-tert·butyl ester

Preparation Products

Methotrexate α-tert-Butyl Ester Suppliers

Global( 20)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Honeychem Pharma Research 08048250387Ext 379 Karnataka, India 66 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 5225 58 Inquiry
Tianjin shanhaijing medicine technology co., ltd 19129375004 15321929114 China 503 58 Inquiry
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 China 2956 58 Inquiry
ChemShuttle, Inc. 0510-83588313-802 18800520310; China 2996 62 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9721 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 China 12308 58 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; China 29778 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Honeychem Pharma Research 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58
Tianjin shanhaijing medicine technology co., ltd 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
ChemShuttle, Inc. 62
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
MedChemExpress 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Methotrexate α-tert-Butyl Ester (S)-5-(tert-butoxy)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-(1,1-dimethylethyl) ester Methotrexate a-tert-Butyl Ester Methotrexate α-tert-Butyl Ester Methotrexate Impurity 8 79640-70-3