Monensin sodium salt
- CAS No.
- 22373-78-0
- Chemical Name:
- Monensin sodium salt
- Synonyms
- Coban;RUMENSIN;Coban45;Sodiummonensin;Monomycin sodium;MONENSINSODIUM,USP;Monensin sodium 40%;Monensin sodium salt;Previouscas:22136-43-2;Monensin sodium, 90-95%
- CBNumber:
- CB7748020
- Molecular Formula:
- C36H63NaO12
- Molecular Weight:
- 710.87
- MOL File:
- 22373-78-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | 267-269 C |
|---|---|
| alpha | 57.3 º (c=4.0, in MeOH) |
| storage temp. | 2-8°C |
| solubility | Soluble in methanol at 50mg/ml |
| form | Off-white to beige solid |
| color | White |
| BRN | 4122200 |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| InChIKey | XOIQMTLWECTKJL-BEMBKCOJSA-M |
| LogP | 3.716 (est) |
| EPA Substance Registry System | Monensin, monosodium salt (22373-78-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300-H319-H334-H373-H411 | |||||||||
| Precautionary statements | P260-P264-P273-P301+P310-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | T,T+ | |||||||||
| Risk Statements | 25-26/27/28 | |||||||||
| Safety Statements | 36/37/39-45-22 | |||||||||
| RIDADR | UN 3462 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | JH2830000 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29419090 | |||||||||
| NFPA 704 |
|
Monensin sodium salt price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M5273 | Monensin sodium salt 90-95% (TLC) | 22373-78-0 | 500MG | ₹7783.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M5273 | Monensin sodium salt 90-95% (TLC) | 22373-78-0 | 1G | ₹12167.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2775 | Monensin Sodium Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 300?mg | 22373-78-0 | 300MG | ₹14473.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M5273 | Monensin sodium salt 90-95% (TLC) | 22373-78-0 | 5G | ₹45378.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46468 | Monensin sodium salt hydrate VETRANAL?, analytical standard | 22373-78-0 | 100MG | ₹5585.7 | 2022-06-14 | Buy |
Monensin sodium salt Chemical Properties,Uses,Production
Description
Monensin is a naturally occuring ionophorous antibiotic that preferentially forms complexes with monovalent cations to enable transport across lipid membranes. Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria such as Micrococcus, Bacillus, and Staphylococcus (MICs = 1-12.5 μg/ml), reduce proliferation of P. falciparum and Coccicdium protozoa, and also prevent replication of certain viruses.
Chemical Properties
LIGHT CREAM AMORPHOUS POWDER
Uses
Monensin sodium salt is used in potentiometric and spectroscopic studies of alkali metal ion complexes. Monensin (Na) is a polyether small molecule ionophore, capable of forming stable complexes to monovalent cations with specific affinity for Na+. Monensin presents a highly lipophilic scaffold around the bound ion, allowing movement of the complex through the lipid bilayer and consequent transport of the ion out of the cell. Excessive flux of ions out of the cell produces a cytotoxic effect and generates the antibiotic properties of Monensin.
General Description
Monensin is a polyether ionophoric antibiotic, which is produced by Streptomyces cinnamonensis. It is used to treat bacterial, fungal and parasitic infections. Monensin prevents the growth of colon cancer cells. It facilitates the transport of sodium and potassium ions between intracellular and extracellular spaces. Monensin prevents coccidiosis?in poultry production.
Purification Methods
Crystallise it from EtOH/H2O [Cox et al. J Am Chem Soc 107 4297 1985].
Monensin sodium salt Preparation Products And Raw materials
Global( 346)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12458 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | China | 5835 | 58 | Inquiry |
22373-78-0(Monensin sodium salt)Related Search:
Coban45
gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alphmonosod
methyl-5-(tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2h-pyran-2-yl)-2
monensin,monosodiumsalt
Monensin,monosodiumsalt(9CI)
Previouscas:22136-43-2
Sodiummonensin
2-[5-Ethyltetrahydro-5-[tetrahydro-3-Methyl-5-[tetrahydro-6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-Methoxy-α,γ,2,8-tetraMethyl-
MONENSIN SODIUM (Monensin A is shown)
1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, monosodium salt (8CI)
Monensin sodium, 90-95%
1,6-Dioxaspiro[4.5]decane-7-butyricacid,2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-,monosodiumsal
1,6-Dioxaspiro[4.5]decane-7-butyricacid,2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-,monosodiumsalt
MONENSIN SODIUM SALT 97%
MONENSIN SODIUM SALT HYDRATE
MONENSINSODIUM,USP
1,6-Dioxaspiro[4.5] decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5- [tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9- hydroxy-.beta.-methoxy-.alpha.,.gamma.-2,8-tetramethyl-, monosodium salt
4-[2-[5-Ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-oxan-2-yl]-3-methyl-oxolan-2-yl]oxolan-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methyl-pentanoic acid monosodium salt
Monensin, sodium salt,97%
1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydrox y-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-metho xy-.alpha.,.gamma.,2,8-tetramethyl-, monosodium salt (8CI
Sodium 4-[2-[2-Ethyl-3'-methyl-5'-(tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethylpyran-2-yl)perhydro-2,2'-bifuran-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl}-3-methoxy-2-methylpentanoate
Monensin Sodium (200 mg)
Monensin sodium salt,Monensin A sodium salt
Monensin sodiuM salt(Coban)
Monensin sodium salt
Monensin sodium 40%
2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-Dioxaspiro[4.5]decane-7-butyric acid sodium salt
Monensin, Sodium Salt, High Purity - CAS 22373-78-0 - Calbiochem
Monensin sodium salt, 90+ %
Monensin sodium salt USP/EP/BP
Sodium (2S,3R,4S)-4-((2S,5R,7S,8R,9S)-2-((2S,2'R,3'S,5R,5'R)-2-ethyl-5'-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-3'-methyloctahydro-[2,2'-bifuran]-5-yl)-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methoxy-2-methylpentanoate
Sodium (2S,3R,4S)-4-((2S,5R,7S,8R,9S)-2-((2S,2'R,3'S,5R,5'R)-2-ethyl-5'-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-3'-methyloctahydro-[2,2'-bifuran]-5-yl)-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methox
Monensin Sodium Salt (MSN), 90-95%
Sodium (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-2-Ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-[2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-
Monensin sodium 20/40%/90%
Coban
RUMENSIN
Monomycin sodium
Sodium Monensin|||Monensin A sodium salt
22373-78-0
C36H61NaO11
C36H63NaO12
C36H61NaO11xH2O
Antibiotics
Antibiotics A to Z
Antibiotics G-M
BioChemical
Inhibitors
Organics
Chiral Reagents
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
22373-78-0