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1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Structure
CAS No.
39235-58-0
Chemical Name:
1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE
Synonyms
Salbutamol Impurity 50;Ibandronate Impurity 28;4-hydroxy-3-hydroxymethylacetophenone;1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE;Ethanone, 1-[4-hydroxy-3-(hydroxymethyl)phenyl]-
CBNumber:
CB7750047
Molecular Formula:
C9H10O3
Molecular Weight:
166.17
MOL File:
Mol file
Modify Date:
2023/4/23 13:52:06
Request For Quotation

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Properties

Melting point 121 °C
Boiling point 381.4±32.0 °C(Predicted)
Density 1.247±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Acetone, Chloroform
form Solid
pka 8.13±0.18(Predicted)
color Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Chemical Properties,Uses,Production

Uses

1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-ethanone is an intermediate in synthesizing Albuterol Dimer Ether (A514520), which is an impurity of Albuterol (Salbutamol) (A514500). Albuterol impurity F. Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic.

Preparation

Obtained by refluxing 3-chloromethyl-4-hydroxy-acetophenone with water for 3 h (70%).

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3-CHLOROMETHYL-4-HYDROXY-PHENYL)-ETHANONE 4-Acetoxy-3-acetoxymethylacetophenone

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Suppliers

Global( 40)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Changzhou Ditong Chemical Co.,Ltd +86-0519-88299272 China 2169 58 Inquiry
Aromsyn Co., Ltd. +86-0571-85585865 +8613336024896 China 19185 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48465 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
Heyuan broad spectrum Biotechnology Co., Ltd 0762-3393039 18023108599 China 984 58 Inquiry
Nanjing Chemlin Chemical Co., Ltd 025-83697070 China 19169 64 Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 China 40037 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Changzhou Ditong Chemical Co.,Ltd 58
Aromsyn Co., Ltd. 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
Heyuan broad spectrum Biotechnology Co., Ltd 58
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Haohong Pharmaceutical Co., Ltd. 58
1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE 4-hydroxy-3-hydroxymethylacetophenone Ethanone, 1-[4-hydroxy-3-(hydroxymethyl)phenyl]- Salbutamol Impurity 50 Ibandronate Impurity 28 39235-58-0