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(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid

(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid Structure
CAS No.
1492-08-6
Chemical Name:
(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid
Synonyms
R-Mevalonic acid-5-Pyrophosphate;(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid
CBNumber:
CB81236237
Molecular Formula:
C6H14O10P2
Molecular Weight:
0
MOL File:
1492-08-6.mol
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(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid Chemical Properties,Uses,Production

Purification Methods

Purify the pyrophosphate by ion-exchange chromatography on Dowex-1 formate [Bloch et al. J Biol Chem 234 2595 1959], DEAE-cellulose [Skilletar and Kekwick, Anal Biochem 20 171 1967], or by paper chromatography [Rogers et al. Biochem J 99 381 1966]. Likely impurities are ATP and mevalonic acid phosphate. Store it as a dry powder or in a slightly alkaline (pH 7-9) solution at -20o.

(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

ISOPENTENYL PYROPHOSPHATE AMMONIUM 200
(3R)-3-hydroxy-5-(hydroxy(phosphonooxy)phosphoryloxy)-3-methylpentanoic acid R-Mevalonic acid-5-Pyrophosphate 1492-08-6