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(3,4-Dimethoxyphenyl)isopropyl ketone

(3,4-Dimethoxyphenyl)isopropyl ketone Structure
CAS No.
14046-55-0
Chemical Name:
(3,4-Dimethoxyphenyl)isopropyl ketone
Synonyms
Nsc63844;Verapamil Impurity L;Verapamil EP Impurity L;verapamil impurities879;3',4'-Dimethoxyisobutyrophenone;Isobutyrophenone, 3',4'-dimethoxy-;1-(3,4-Dimethoxyphenyl)-2-methylpro;(3,4-Dimethoxyphenyl)isopropyl ketone;3',4'-DIMETHOXY-2-METHYLPROPIOPHENONE;Verapamil Hydrochloride EP Impurity L
CBNumber:
CB82217071
Molecular Formula:
C12H16O3
Molecular Weight:
208.25
MOL File:
14046-55-0.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:12:35

(3,4-Dimethoxyphenyl)isopropyl ketone Properties

Boiling point 165-170℃ (10 Torr)
Density 1.029±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Sparingly), Methanol (Slightly)
form Oil
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H315-H302-H335
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

(3,4-Dimethoxyphenyl)isopropyl ketone Chemical Properties,Uses,Production

Uses

1-(3,4-Dimethoxyphenyl)-2-methyl-1-propanone (Verapamil EP Impurity L) is a compound being considered as an inhibitor of melanogenesis. It may reduce growth or pigment production in melanocyte cells.

Preparation

Preparation by acylation of veratrole,
with isobutyryl chloride in the presence of aluminium chloride (85%)
with isobutyric acid in the presence of PPA at 60° for 2.5 h
with isobutyric anhydride in acetonitrile in the presence of TiCl(OTf)3 /TfOH at r.t. for 12 h (89%).

(3,4-Dimethoxyphenyl)isopropyl ketone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 38)Suppliers
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(3,4-Dimethoxyphenyl)isopropyl ketone 1-(3,4-Dimethoxyphenyl)-2-methyl-1-propanone 3',4'-Dimethoxyisobutyrophenone 1-Propanone, 1-(3,4-dimethoxyphenyl)-2-methyl- Isobutyrophenone, 3',4'-dimethoxy- Nsc63844 Verapamil Impurity L Verapamil Impurity 12(Verapamil EP Impurity L) 3',4'-DIMETHOXY-2-METHYLPROPIOPHENONE Verapamil EP Impurity L 1-(3,4-Dimethoxyphenyl)-2-methylpro verapamil impurities879 Verapamil Hydrochloride EP Impurity L 1-(3,4-Dimethoxyphenyl)-2-methylpropan-1-one (Verapamil Impurity) 14046-55-0