Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Structure
CAS No.
19667-37-9
Chemical Name:
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
Synonyms
Rivaroxaban Impurity 120;N-(3-Chloro-2-hydroxypropyl)phthalimide;2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione;2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-
CBNumber:
CB82356277
Molecular Formula:
C11H10ClNO3
Molecular Weight:
239.65
MOL File:
19667-37-9.mol
Modify Date:
2023/5/4 15:14:15
Request For Quotation

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Properties

Melting point 95-96.5 °C
Boiling point 405.4±35.0 °C(Predicted)
Density 1.444±0.06 g/cm3(Predicted)
pka 13.25±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Chemical Properties,Uses,Production

Uses

2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-?MS?/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance.

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Suppliers

Global( 25)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SYNGREEN LIFESCIENCES PVT.LTD +919849474297 Telangana, India 82 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 China 5000 58 Inquiry
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 China 7969 58 Inquiry
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 China 49323 58 Inquiry
Wuhan kemike Biomedical Technology Co., Ltd 027-87747081 18186681184 China 7243 58 Inquiry
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 China 50471 58 Inquiry
Aikon International Limited 18626450290 China 10718 58 Inquiry
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 China 3083 55 Inquiry
Supplier Advantage
SYNGREEN LIFESCIENCES PVT.LTD 58
sgtlifesciences pvt ltd 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 58
Hubei Kele Fine Chemical Co., Ltd 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Wuhan kemike Biomedical Technology Co., Ltd 58
Beijing Solarbio Science & Tecnology Co., Ltd. 58
Aikon International Limited 58
Shanghai ChuangYan Chemical Technology Co., Ltd. 55
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione N-(3-Chloro-2-hydroxypropyl)phthalimide 2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)- Rivaroxaban Impurity 120 19667-37-9 19667-37-2