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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Protein tyrosine kinase /JAK / STAT >JAK inhibitors >N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide Structure
CAS No.
936091-14-4
Chemical Name:
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide
Synonyms
CS-94;TG101209, >=99%;TG101209/TG-101209;TG101209;TG 101209;TG-101209;N-tert-Butyl-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzenesul;N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide;Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-;Cluster of differentiation antigen 135,RET,TG101209,Inhibitor,Janus kinase,CD135,Fms like tyrosine kinase 3,TG 101209,FLT3,TG-101209,Apoptosis,JAK,inhibit,Autophagy
CBNumber:
CB82485001
Molecular Formula:
C26H35N7O2S
Molecular Weight:
509.67
MOL File:
936091-14-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:20
Request For Quotation

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide Properties

Melting point 243 °C
Boiling point 703.1±70.0 °C(Predicted)
Density 1.250
storage temp. Store at -20°C
solubility ≥25.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form solid
pka 11.95±0.50(Predicted)
color White to gray

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P260-P264-P270-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501
NFPA 704
0
2 0

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide Chemical Properties,Uses,Production

Uses

TG101209 is an effective tyrosine kinase inhibitor of tyrosine kinases JAK2 and JAK3 (janus kinase 2/3), inducing cell arrest and apoptosis in leukemia cell lines.

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide Suppliers

Global( 129)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
LEAP CHEM CO., LTD. 58

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide Spectrum

N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide(936091-14-4)1HNMR

936091-14-4(N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide)Related Search:

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5-PYRIDIN-4-YL-1H-INDAZOLE 3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol TG6-10-1 N-(tert-Butyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide SGI 7079
Gilteritinib ABX-1431 N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
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TG101209, >=99% N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide TG101209/TG-101209 N-tert-Butyl-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzenesul TG101209;TG 101209;TG-101209 CS-94 Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]- Cluster of differentiation antigen 135,RET,TG101209,Inhibitor,Janus kinase,CD135,Fms like tyrosine kinase 3,TG 101209,FLT3,TG-101209,Apoptosis,JAK,inhibit,Autophagy 936091-14-4 C26H35N7O2S JAK STAT Inhibitors Inhibitor API